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https://www.youtube.com/watch?v=q6uCIgWQkwM
Feb 06, 2017 · Direct transport of drug through nose to brain by passing BBB. Skip navigation ... Intranasal (nose to brain) drug delivery system Sagar Savale. ... An Overview of Intrathecal Drug Delivery ...Author: Sagar Savale
https://www.omicsonline.org/open-access/nose-to-brain-drug-delivery-a-recent-update.pdf
Nose to Brain Drug Delivery: A Recent UpdateAuthor: Bappaditya Chatterjee
https://www.youtube.com/watch?v=Cuzs-lwmfEs
Feb 08, 2017 · It is direct pathway for transport of drug nose to brain by passing BBB. ... Nose to Brain Drug Delivery System Sagar Savale. ... Increasing drug delivery through the blood-brain barrier ...Author: Sagar Savale
https://en.wikipedia.org/wiki/Nasal_administration
Nasal administration is a route of administration in which drugs are insufflated through the nose.It can be a form of either topical administration or systemic administration, as the drugs thus locally delivered can go on to have either purely local or systemic effects.Nasal sprays are locally acting drugs such as decongestants for cold and allergy treatment, whose systemic effects are usually ...
http://intranasal.net/AnatomyPhysiology/default.htm
Multiple authors demonstrate that the nose-brain pathway leads to nearly immediate delivery of some nasal medications to the cerebral spinal fluid, by-passing the blood brain barrier.[5-9,11, 12] Literature related to Nose brain pathway: Talegaonkar, IN delivery and BBB, Indian J Pharm 2004.pdf
https://www.hindawi.com/journals/isrn/2013/238428/
As a consequence, several strategies are currently being sought after to enhance the delivery of drugs across the BBB. Within this review, the recently born strategy of brain drug delivery based on the use of nanoparticles, multifunctional drug delivery systems with size …
https://cyqoqu.files.wordpress.com/2015/06/nose-to-brain-drug-delivery-pdf.pdf
nose to brain drug delivery.pdf Drug delivery of these therapeutic proteins is facing several challenges. ... nose to brain drug delivery system ppt The nose may help the brain.Introduction: The bloodbrain barrier BBB represents a stringent barrier for delivery of neurotherapeutics in vivo. An attempt to overcome this barrier is.General methods ...
https://www.dhs.wisconsin.gov/ems/training/2014emrnaloxoneppt.pptx
Nose brain pathway. The olfactory mucosa (smelling area in nose) is in direct contact with the brain and cerebrospinal fluid (CSF). Medications absorbed across the olfactory mucosa directly enter the CSF. This area is termed the nose brain pathway and offers a rapid, direct route for drug delivery to the brain. Olfactory mucosa, nerve
http://www.authorstream.com/Presentation/wolfeman8-283260-intranasal-drugs-ems-medications-prehospital-needle-stick-seizure-pain-part-2-nasal-drug-delivery-education-ppt-powerpoint/
Intranasal Medication Administration: Basic Concepts : Intranasal Medication Administration: Basic Concepts This delivery route has several advantages: Its easy and convenient Almost everyone has a nose The nose is a very easy access point for medication delivery (even easier than the arm, especially in winter) No special training is required to deliver the medication No shots are needed It is ...
https://www.sciencedirect.com/book/9780128140017/brain-targeted-drug-delivery-system
Brain targeting drug delivery has been gained increasing attention in the past decade, and many strategies were developed to improve the brain targeting drug delivery by fabricating various nanoparticles-based drug delivery systems. Although impressive progress has been made, the drug delivery efficiency is still far from satisfactory.
https://www.sciencedirect.com/science/article/pii/S2211383513000178
For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery technologies to improve the effectiveness of inner ear drug therapy.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108880
Central nervous system (CNS) diseases are difficult to treat because of the blood-brain barrier (BBB), which prevents most drugs from entering into the brain. Intranasal (IN) administration is a promising approach for drug delivery to the brain, bypassing the BBB; however, its application has been restricted to particularly potent substances and it does not offer localized delivery to specific ...
https://www.youtube.com/watch?v=o4moymWepUg
Feb 17, 2015 · Robert S. Langer (MIT) Part 2: Drug Delivery Technology: Present and Future ... a porous polymer can be shaped into an ear or nose and act as a scaffold onto which a patient’s cells can be ...Author: iBiology
https://www.intechopen.com/books/drug-discovery-and-development-from-molecules-to-medicine/intranasal-drug-administration-an-attractive-delivery-route-for-some-drugs
Drug, particles: consideration should be given to the desired therapeutic concentration for each dose, keeping in mind whether the total dose to the nasal cavity will be one (single nostril delivery) or two (one delivery into each nostril). For aqueous solutions and suspensions the typical dosing volume ranges are 50-140µl and for solution or ...
https://www.springer.com/journal/13346
Exclusively focused on translational aspects of drug delivery, this journal provides a unique forum for publication of high-quality research. Drug Delivery and Translational Research publishes research focused on such topics as designing and developing novel drug delivery systems, with a focus on their application to disease conditions; preclinical and clinical data related to drug delivery ...
https://pharma.aptar.com/en-us/dispensing-solutions/uds.html
Our range of UDS, and in particular the UDS powder, is designed to address the nose-to-brain pathway. Dry powder formulations bring additional benefits, such as lack of preservatives, administration of larger doses of drugs and the improved stability of the formulation. Key Features. Accurate one shot drug delivery
https://pharma.aptar.com/sites/default/files/publications/bbbreprint.pdf
with regard to effectively crossing the blood brain barrier (BBB) and successfully treating a host of CNS diseases. ... facing drug delivery across the BBB and into the CNS - the result of a natural evolution over many millennia and a barrier ... Figure 4 : Nasal cavity and regions of interest for nose to brain delivery.
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