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https://www.sciencedirect.com/science/article/pii/S0302283806009687
Indeed, a better knowledge of urothelial permeability and of new systems of delivery could help to optimise intravesical treatments. This review examines the mechanisms underlying drug transport into the bladder wall and discusses exciting new frontiers for intravesical therapy. 2. Bladder urothelium: permeability and drug diffusionAuthor: Antonella Giannantoni, Savino M. Di Stasi, Michael B. Chancellor, Elisabetta Costantini, Massimo Por...
https://www.researchgate.net/publication/6827772_New_Frontiers_in_Intravesical_Therapies_and_Drug_Delivery
Electromotive drug administration, new in situ delivery systems, and bioadhesive liposomes may make it possible to extend intravesical therapy and drug administration to many bladder diseases.
https://www.europeanurology.com/article/S0302-2838(06)00968-7/fulltext
Aug 30, 2006 · Intravesical route permits site-specific delivery of drugs with a reduced side-effect profile as compared to oral delivery systems. This review investigates new physical and chemical approaches in intravesical drug delivery that potentially permit successful treatment of several bladder dysfunction.Author: Antonella Giannantoni, Savino M. Di Stasi, Michael B. Chancellor, Elisabetta Costantini, Massimo Por...
https://www.europeanurology.com/article/S0302-2838(06)00968-7/pdf/new-frontiers-in-intravesical-therapies-and-drug-delivery
Review – Voiding Dysfunction New Frontiers in Intravesical Therapies and Drug Delivery Antonella Giannantonia,*, Savino M. Di Stasib, Michael B. Chancellorc, Elisabetta Costantinia, Massimo Porenaa a Department of Urology, University of Perugia, Perugia, Italy b Department of Urology, ‘‘Tor Vergata’’ University of Rome, Rome, Italy c McGowan Institute of Regenerative Medicine ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219302/
Jul 12, 2014 · We determined the effect of intravesical instillation of pentosan polysulfate encapsulated in liposomes for refractory interstitial cystitis patients. This was an open label uncontrolled study. Subjects were recruited from a private urology practice. ...Author: Elliot B Lander, Jackie R See
https://core.ac.uk/display/53823744
Liposomes improve the aqueous solubility of several hydrophobic drugs such as taxol, amphotericin, and capsaicin. Conclusions: Electromotive drug administration, new in situ delivery systems, and bioadhesive liposomes may make it possible to extend intravesical therapy …Author: Antonella Giannantoni, Savino M. Di Stasi, Michael B. Chancellor, Elisabetta Costantini, Massimo Por...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1476022/
New Frontiers in the Treatment of Overactive Bladder and Incontinence. ... The author also discusses intravesical therapy and alternative drug delivery methods, such as intravesical capsaicin and botulinum toxin. There are many advantages to advanced drug delivery systems, including the achievement of long-term therapeutic efficacy, decreased ...Author: Michael B Chancellor
https://www.future-science.com/doi/10.4155/tde.14.25
The human urothelium belongs to the most efficient biobarriers, and represents a highly rewarding but challenging target for local drug administration. Inadequate urothelial bioavailability is a ma...Author: Lukas Neutsch, Franz Gabor, Michael Wirth
https://www.sciencedirect.com/science/article/pii/S016836591631224X
Urothelium-adherent, ion-triggered liposome-in-gel system as a platform for intravesical drug delivery. ... M.B. Chancellor, E. Costantini, M. PorenaNew frontiers in intravesical therapies and drug delivery. Eur. Urol., 50 (2006), pp. 1183-1193 (discussion 1193)Author: Shruti GuhaSarkar, Prachi More, Rinti Banerjee
https://www.frontiersin.org/articles/10.3389/fphar.2017.00977/full
Jan 12, 2018 · There are no established effective intravesical therapies available for patients, whose tumors recur following BCG treatment, representing an important unmet clinical need. ... Frontiers in Pharmacology ... The development of new drug delivery systems has been growing and is expected to continue to increase over the next few years ...Author: Julieti Huch Buss, Karine Rech Begnini, Camila Bonemann Bender, Adriana R. Pohlmann, Silvia S. Guter...
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