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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The aims for nanoparticle entrapment of drugs are either enhanced delivery to, or uptake by, target cells and/or a reduction in the toxicity of the free drug to non-target organs. Both situations will result in an increase of therapeutic index, the margin between the doses resulting in a therapeutic efficacy (eg,...Author: Wim H De Jong, Paul Ja Borm
https://www.nature.com/articles/s41467-019-11718-4
Aug 23, 2019 · Nanoparticles-based drug delivery systems (NDDSs) have shown promising therapeutic efficacy in cancer due to the enhanced permeability and retention (EPR) effect 1,2.To increase the capacity of ...Author: Tuying Yong, Xiaoqiong Zhang, Nana Bie, Hongbo Zhang, Xuting Zhang, Fuying Li, Abdul Hakeem, Jun Hu,...
https://www.nature.com/articles/s41598-018-21331-y
Feb 13, 2018 · Colloidal gold nanoparticles (AuNPs) are of interest as non-toxic carriers for drug delivery owing to their advanced properties, such as extensive surface-to-volume ratio and possibilities for tailoring their charge, hydrophilicity and functionality through surface chemistries.Author: Muhammad U. Farooq, Valentyn Novosad, Valentyn Novosad, Elena A. Rozhkova, Hussain Wali, Asghar Ali,...
https://www.news-medical.net/news/20191105/Researchers-successfully-treat-pain-using-nanoparticles-to-deliver-a-non-opioid-pain-medication.aspx
Nov 05, 2019 · Using nanoparticles to target the endosome for drug delivery. As reported in the journal Nature Nanotechnology, the researchers have now used nanoparticles as vesicles to …
https://www.nature.com/articles/s41598-020-63234-x
Microfluidics is considered a disruptive technology for pharmaceutical manufacturing and is becoming a gold standard in the production of nanoparticles for drug delivery.
https://www.nature.com/articles/s41467-020-14972-z
Mar 09, 2020 · This approach is becoming increasingly prominent for diagnosis and treatment of cancer, anemia, diabetes, and Alzheimer’s disease via nano-enabled biosensors, bioimaging, and drug delivery …Author: Yu Qi, Yu Qi, Tong Zhang, Chuanyong Jing, Sijin Liu, Chengdong Zhang, Chengdong Zhang, Pedro J. J. A...
https://www.nature.com/articles/srep20867
Feb 15, 2016 · It is a challenge to eradicate tumor cells while sparing normal cells. We used magnetoelectric nanoparticles (MENs) to control drug delivery and release. The physics is due to electric-field interactions (i) between MENs and a drug and (ii) between drug-loaded MENs and cells.Author: Alexandra Rodzinski, Rakesh Guduru, Ping Liang, Ali Hadjikhani, Tiffanie Stewart, Emmanuel Stimphil,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES Considerable research and development is devoted to improving drug delivery through the use of nanoparticles.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978509/
Currently, the field of nanoparticle-based drug delivery is extending beyond the confines of convention (e.g., traditional geometries, sizes or chemistries) so as to rationally design entities specifically tasked with overcoming sequential biological barriers . There is the growing realization that although the distinct obstacles that hinder adequate delivery of therapeutics to tumors are indeed complex, they are by no …Author: Elvin Blanco, Haifa Shen, Haifa Shen, Mauro Ferrari, Mauro Ferrari
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