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https://www.optinose.com/exhalation-delivery-systems/nasal-delivery-challenges
Nasal Delivery Challenges Despite easy access, the complex and dynamic geometry of the nose makes reliable and efficient delivery of drugs to mucosal surfaces high and deep in the nose challenging. The nasal valve is the narrowest segment of the respiratory tract, accounting for up to 80% of nasal resistance and almost half of total respiratory resistance.
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/nasal/
Your patients deserve better nasal drug delivery than aqueous nasal sprays for allergic rhinitis. These sprays can drip down the throat and out of the nose, causing irritation, embarrassment, and unpleasant aftertastes. 3M can help deliver your treatments with intuitive patient-friendly nasal MDIs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland
https://www.contractpharma.com/issues/2019-01-01/view_features/nasal-drug-delivery
Nasal Drug Delivery. Nasal spray devices are used to deliver both locally and systemically acting pharmaceutical products, 1 and are readily available in the marketplace in …
https://www.ondrugdelivery.com/wp-content/uploads/2018/11/Nov2005.pdf
Direct-Haler A/S has invented and developed a novel nasal delivery device and nasal delivery principle. The innovation takes advantage of the patient’s anatomy to improve nasal delivery effectiveness and convenience. The integrated nasal device and delivery method enables nasal delivery of very fine particles, without the risk of pulmonary deposition.
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