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https://www.optinose.com/exhalation-delivery-systems/nasal-delivery-challenges
Nasal Delivery Challenges Despite easy access, the complex and dynamic geometry of the nose makes reliable and efficient delivery of drugs to mucosal surfaces high and deep in the nose challenging. The nasal valve is the narrowest segment of the respiratory tract, accounting for up to 80% of nasal resistance and almost half of total respiratory ...
https://www.businesswire.com/news/home/20190813005289/en/Global-Intranasal-Drug-Delivery-Market-Report-2019
Aug 13, 2019 · Global Intranasal Drug Delivery Market Report 2019: Analysis, Trends, and Forecasts 2016-2024 - Focus on Allergic Infections, Analgesics, Osteoporosis, Vaccinations - ResearchAndMarkets.com
https://www.ncbi.nlm.nih.gov/pubmed/21325837
Nasal drug delivery in humans. Bitter C, Suter-Zimmermann K, Surber C. Intranasal administration is an attractive option for local and systemic delivery of many therapeutic agents. The nasal mucosa is--compared to other mucosae--easily accessible.Author: Christoph Bitter, Katja Suter-Zimmermann, Christian Surber
https://www.cpap-supply.com/Aclaim-2-Nasal-Mask-p/hc401.htm
Aclaim 2 Nasal Mask with Headgear In Stock Now! Prescription Required. Parts Available without Prescription. CPAP nasal mask for CPAP or bi-level ventilation. Includes two silicone cushion sizes so that you don't need to select a size. Also includes a spare diffuser.4/5(19)
https://www.researchgate.net/publication/49840496_Nasal_Drug_Delivery_in_Humans
Intranasal administration is an attractive option for local and systemic delivery of many therapeutic agents. The nasal mucosa is--compared to other mucosae--easily accessible.
Gamma camera images after using a traditional nasal spray device or an Optinose Exhalation Delivery System. Both images are from the same subject and are representative of the overall findings from 211 images and 56 subjects. The clinical relevance of different deposition patterns has not been established.
http://intranasal.net/DeliveryTechniques/default.htm
Squeeze bottle delivery is another option for nasal drug delivery. However this technique is not able to deliver a measure dose of drug. Mucosal coverage is also dependent on the patient applying adequate pressure to the device to deliver the drug - so delivery is very variable.
https://prod.med.uth.edu/orl/2020/02/16/new-nonsurgical-treatments-for-nasal-polyps-help-patients-breathe-again/
New Nonsurgical Treatments for Nasal Polyps Help Patients Breathe Again. Internationally recognized rhinologist Martin J. Citardi, MD, professor and chair of the Department of Otorhinolaryngology-Head and Neck Surgery at McGovern Medical School, does his utmost to help patients with nasal polyps avoid sinus surgery.That commitment has led him to explore innovative topical treatments, steroid ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668946/
Midazolam's small molecular weight of 325.8 Da allows for easy permeation of nasal mucosa. 6 Midazolam dissolves in water at a low pH, but at physiologic pH it becomes lipophilic, allowing the medication to cross the blood-brain barrier. 4, 7 Rey and colleagues 9 studied the pharmacokinetics of intranasal midazolam in 6 children (ages 1–5 years) and found the time to maximum concentration to ...
https://shenclinic.com/products/nasal-tabs
Nasal Tabs 2 / Health Concerns Chinese Herbs Supporting Nasal And Sinus Health* Free Gift Included with Nasal Tabs 2. Also See Dr. Shen's Sinus & Nose Pills. Augmented QING BI TANG Releases The Surface, Vitalizes Blood, And Dispels Wind Health Concerns Nasal Tabs are a Xanthium based formula to support normal breathing when nose and sinuses are stressed by allergies and irritants.
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