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https://www.ondrugdelivery.com/wp-content/uploads/2018/11/Nov2005.pdf
Direct-Haler A/S has invented and developed a novel nasal delivery device and nasal delivery principle. The innovation takes advantage of the patient’s anatomy to improve nasal delivery effectiveness and convenience. The integrated nasal device and delivery method enables nasal delivery of very fine particles, without the risk of pulmonary ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930669/
Nov 26, 2019 · In particular, the specific properties of nanomedicines proposed for nose-to-brain delivery will be critically evaluated. The preclinical and clinical data considered supporting the idea that nasal delivery of anticancer drugs may represent a breakthrough advancement in the fight against GBM.Author: Franciele Aline Bruinsmann, Gustavo Richter Vaz, Aline de Cristo Soares Alves, Tanira Aguirre, Adria...
https://www.businesswire.com/news/home/20190813005289/en/Global-Intranasal-Drug-Delivery-Market-Report-2019
Aug 13, 2019 · Global Intranasal Drug Delivery Market Report 2019: Analysis, Trends, and Forecasts 2016-2024 - Focus on Allergic Infections, Analgesics, Osteoporosis, Vaccinations - ResearchAndMarkets.com
https://www.optinose.com/exhalation-delivery-systems/nasal-delivery-challenges
Despite easy access, the complex and dynamic geometry of the nose makes reliable and efficient delivery of drugs to mucosal surfaces high and deep in the nose challenging. The nasal valve is the narrowest segment of the respiratory tract, accounting for up to 80% of nasal resistance and almost half of total respiratory resistance.
https://www.contractpharma.com/issues/2019-01-01/view_features/nasal-drug-delivery
One of the benefits of nasal delivery for systemic drugs is that they can bypass the blood-brain barrier and enter the brain directly via the olfactory and trigeminal nerve pathways. 2-4 Additionally, the nasal cavity has a thin, well vascularised mucosa. 5 Drug molecules can transfer across this layer directly to the systemic blood circulation ...
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/nasal/
Your patients deserve better nasal drug delivery than aqueous nasal sprays for allergic rhinitis. These sprays can drip down the throat and out of the nose, causing irritation, embarrassment, and unpleasant aftertastes. 3M can help deliver your treatments with intuitive patient-friendly nasal MDIs.
https://www.mdpi.com/1420-3049/14/9/3754/htm
Nasal drug delivery may be used for either local or systemic effects. Low molecular weight drugs with are rapidly absorbed through nasal mucosa. The main reasons for this are the high permeability, fairly wide absorption area, porous and thin endothelial basement membrane of the nasal epithelium. Despite the many advantages of the nasal route, limitations such as the high molecular weight (HMW ...Author: Yıldız Ozsoy, Sevgi Gungor, Erdal Cevher
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