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https://www.researchgate.net/publication/49840496_Nasal_Drug_Delivery_in_Humans
Nasal Drug Delivery in Humans. ... tem and delivery device – is the basis of a successful formulation development. ... for a controlled delivery through nasal route via liposomes of an active ...
https://pharma.aptar.com/en-us/delivery-routes/nasal.html
Either for prevention or final symptom relief, a wide range of delivery solutions needs to be provided. As a market leader in OTC nasal sprays and other devices and services, we provide various systems to administer these remedies in a convenient and user-friendly way. Our modular product platform allows for serving individual market requirements.
http://jpet.aspetjournals.org/content/370/3/593
Drugs that are metabolized by nasal cavity enzymes will also need to be protected from degradation, and drug formulations must be non-irritant to the nasal cavity. Furthermore, from a drug development point of view, a nasal delivery device is required to deliver drugs via the nose-to-brain route.
https://www.rch.org.au/rchcpg/hospital_clinical_guideline_index/Oxygen_delivery/
Note: In most low flow systems the flow is usually titrated (on the oxygen flow meter) and recorded in litres per minute (LPM). Where the Airvo2 is used as an oxygen delivery device the flow from this device is independent to the flow of oxygen. High flow delivery method . See also below guidelines for additional information: PICU high flow
https://journals.lww.com/nursing/Fulltext/2003/12000/How_do_I_choose_a_supplemental_oxygen_delivery.24.aspx
Choosing a supplemental oxygen delivery device. My 65-year-old patient has pneumonia. On admission, ... you can choose from among four common oxygen delivery devices. The nasal cannula is a low flow system that mixes oxygen with room air. The flow rates range from 1 to 6 liters/minute, providing 24% to 44% of inspired oxygen. ...
https://www.snbl-nds.com/technology/
SNBL has developed a proprietary nasal drug delivery technology, μco™ System, consisting of a powder carrier technology (μco™ Carrier) designed for increased drug absorption through its muco-adhesive properties and a delivery device technology designed for simple use, and complete and consistent delivery of intranasal powder formulations.
https://www.boundtree.com/Airway-Oxygen-Delivery/Intubation-Aids/MAD-Nasal-Intranasal-Mucosal-Atomization-Devices/p/group000154
The MAD Nasal™ device provides a painless and rapid absorption1 medication delivery option for non-invasive intranasal medication delivery. It increases safety for both caregivers and patients through the avoidance of needlestick injury.
https://www.fortunebusinessinsights.com/industry-reports/nasal-drug-delivery-devices-market-100415
The global nasal drug delivery devices market size was USD 46.34 billion in 2018 and is projected to reach USD 81.85 billion by 2026, exhibiting a CAGR of 7.5% during the forecast period. Nasal drug delivery devices has become one of the most widely researched area through the years.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458852/
Despite the better deposition pattern of the nebulizers, nasal spray is the dominant delivery device in the nasal drug delivery market, being inexpensive and simple to use. It represents the first line of treatment in many nasal conditions, which typically reaches the nasal valve area, the region of maximum resistance to airflow .
http://respwiki.com/FiO2_by_Delivery_Device
Nasal Cannula. The nasal cannula is the most common oxygen delivery device used by patients both at home and in the hospital setting. Unless using a wide bore high flow nasal cannula, the flow rate on a nasal cannula should not exceed 6L/m. The formula to determine the \(FiO_2\) for a nasal cannula is\[FiO_2 = 20+(Flow Rate(L/m)\times4)\]
https://www.contractpharma.com/issues/2019-01-01/view_features/nasal-drug-delivery
Typically, multi-dose metered nasal spray devices have a dip tube going from the actuator into the product. This is to enable liquid product to be delivered when the device is used in an upright orientation. The device will need to be primed by actuating several times to …
https://www.teleflex.com/usa/en/product-areas/emergency-medicine/intranasal-drug-delivery/mad-nasal-intranasal-device/index.html
When IV drug delivery is less than ideal the MAD Nasal ™ Device can come to the rescue delivering safe, painless, and rapidly effective treatment. No shot. No needle. No risk of needle stick injury. MAD Nasal ™ Device Animation Video. MAD Nasal ™ Device Procedure Guide
http://www.kurvetech.com/devices_vianase.asp
ViaNase is an advanced nasal drug delivery system with the ability to optimally saturate the entire nasal cavity. It is also the first device to deliver formulations into the paranasal sinuses in clinical testing. ViaNase offers pharmaceutical companies an effective and efficient delivery for topical, systemic and nose-to-brain therapies.
http://intranasal.net/DeliveryTechniques/default.htm
Squeeze bottle delivery is another option for nasal drug delivery. However this technique is not able to deliver a measure dose of drug. Mucosal coverage is also dependent on the patient applying adequate pressure to the device to deliver the drug - so delivery is very variable.
http://mysticpharmaceuticals.com/delivery-systems/intranasal-delivery-solutions/
VersiDoser® and VRx2™ nasal delivery systems are available in a variety of disposable, reloadable, mono-dose and multi-dose configurations. Each dose is individually packaged in our novel unit dose blister and pre-loaded into a device or into a cartridge that can be easily loaded into the device by the end user prior to use. Our engineered ...
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