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https://epub.uni-regensburg.de/8515/1/ubr04037_ocr.pdf
Formulation and Delivery of Proteins and Peptides Jeffrey L. Cleland, EDITOR Genentech, Inc. Robert Langer, EDITOR Massachusetts Institute of Technology Developed from a symposium sponsored by the Division of Biochemical Technology at the 205th National Meeting of the American Chemical Society, Denver, Colorado, March 28-April 2,1993
https://www.researchgate.net/publication/322468712_Ocular_delivery_of_proteins_and_peptides_Challenges_and_novel_formulation_approaches
Formulation and delivery of proteins and peptides, such as monoclonal antibodies, aptamers, recombinant proteins and peptides to ocular tissues poses significant challenges owing to their large ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995646/
Feb 15, 2018 · The impact of proteins and peptides on the treatment of various conditions including ocular diseases over the past few decades has been advanced by substantial breakthroughs in structural biochemistry, genetic engineering, formulation and delivery …Author: Abhirup Mandal, Dhananjay Pal, Vibhuti Agrahari, Hoang My Trinh, Mary Joseph, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374550/
To improve the patient's compliance and life, many researchers have been working on development of protein and peptide noninvasive route delivery formulation, such as tablet, aerosol, MDI, gel, cream etc. The formulation needs to have newer technology/excipients such as penetration enhancers, polymers, enzyme inhibitors, etc.
https://www.researchgate.net/publication/258149324_Properties_and_formulation_of_oral_drug_delivery_systems_of_protein_and_peptides
Properties and formulation of oral drug delivery systems of protein and peptides Article (PDF Available) in Indian Journal of Pharmaceutical Sciences 69(6):741-747 · December 2007 with 2,642 Reads
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/protein-formulation
Numerous strategies suggested the use of formulation vehicles, such as microemulsions, liposomes, nanoparticles, and microspheres to protect the protein formulation against the harsh environment of the GIT (acidic medium and enzymes) so as to achieve successful delivery of proteins and peptides via the oral route (Wu et al., 2012). These ...
https://www.amazon.com/Therapeutic-Peptides-Proteins-Formulation-Processing/dp/146656606X
Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems, Third Edition provides a comprehensive overview of the field for scientists in industry and academia and for students, while also providing practical information on the challenges facing the formulation and delivery aspects of these unique macromolecules. In ...Author: Ajay K. Banga
https://www.sciencedirect.com/science/article/pii/S0001868617305171
Alternatively, encapsulation of proteins in delivery systems may alter the rate and extent of their hydrolysis in the GIT, thereby controlling the type and location of bioactive peptides generated within the gastrointestinal tract. At present, there have been few studies on the utilization of colloidal delivery systems for this application.Author: David Julian McClements
http://www.pharmtech.com/considering-protein-and-peptide-delivery
Jan 02, 2019 · “Proteins and peptides do not sustain the rigor of the gastrointestinal tract. Chemical degradation in gastric fluids, extensive metabolism in luminal spaces, and first pass metabolism are major concerns with oral delivery of proteins and peptides,” says Nair.
https://www.amazon.com/Pharmaceutical-Formulation-Development-Peptides-Proteins/dp/1439853886
Aug 18, 2014 · Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therapeutic peptides and proteins, from the production of active compounds via basic pre-formulation and formulation to the registration of the final product. Providing integrated solutions, this book discusses:4/4(1)
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