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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The non restricted (cyto)toxicity of chemotherapeutics thus limits the full use of their therapeutic potential. Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as …Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Nanoparticle Delivery Systems. Nanocapsules are vesicular systems in which a drug is confined to a cavity surrounded by a polymer membrane, whereas nanospheres are matrix systems in which the drug is physically and uniformly dispersed.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.sciencedirect.com/science/article/pii/S1734114012709015
Controlled drug delivery systems (DDS) have several advantages compared to the traditional forms of drugs. A drug is transported to the place of action, hence, its influence on vital tissues and undesirable side effects can be minimized.Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://www.medscape.com/viewarticle/770397_1
Nov 06, 2019 · Nanotechnology has the potential to revolutionize drug delivery, but challenges remain. This article summarizes recent developments in the use of nanoparticles as drug delivery systems.
http://if-pan.krakow.pl/pjp/pdf/2012/5_1020.pdf
backs can be overcome by controlling drug delivery. In controlled drug delivery systems (DDS) the drug is transported to the place of action, thus, its influence on vital tissues and undesirable side effects can be minimized. In addition, DDS protects the drug from rapid degradation or clearance and enhances drug
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.hindawi.com/journals/jnm/2016/1087250/
In this paper, we provide an overview of three different targeted drug delivery methods (passive targeting, active targeting, and physical targeting) and compare methods of action, advantages, limitations, and the current stages of research. For the most commonly used …Author: Xiaojiao Yu, Ian Trase, Muqing Ren, Kayla Duval, Xing Guo, Zi Chen
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications** By Igor I. Slowing, Brian G. Trewyn, Supratim Giri, and Victor S.-Y. Lin* 1. Introduction Recent breakthroughs in the synthesis of mesoporous silica materials with controlled particle size, morphology, and porosi-ty, along with their chemical stability, has made ...
https://www.researchgate.net/post/what_are_the_disadvantages_of_nanoparticles_in_drug_delivery
The disadvantages of nanoparticle drug delivery are synonymous with the obstacles researchers are currently trying to overcome. To name a few, immunogenicity, poor site-specific accumulation ...
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