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https://www.sciencedirect.com/science/article/pii/S0168365915301802
This review summarizes marketed protein delivery strategies, recent progress in intracellular protein delivery, design considerations of nanoparticle technologies and their advancement on systemic protein delivery, and the application of nanotechnology to develop non-injectable protein therapeutics that can enhance patient satisfaction and ...Author: Mikyung Yu, Jun Wu, Jinjun Shi, Omid C. Farokhzad, Omid C. Farokhzad
https://www.researchgate.net/publication/6748205_Nanotechnologies_in_Protein_Delivery
Nanotechnologies in Protein Delivery. ... Over the last few decades, several protein delivery sys- tems, including liposome-and polymer-based nanoparticles, bioconjugates, and hydrogels, have been ...
https://www.nature.com/articles/gt20175
Jan 17, 2017 · Because of its safe and effective protein expression profile, in vitro transcribed messenger RNA (IVT-mRNA) represents a promising candidate in the development of …Author: S Guan, J Rosenecker
http://europepmc.org/articles/PMC4833694
Oct 01, 2016 · This review summarizes marketed and developmental-stage protein delivery strategies, recent progress in intracellular protein delivery, design considerations of nanoparticle technologies and their advancement on systemic protein delivery, and the application of nanotechnology to develop non-injectable protein therapeutics that can enhance ...Author: Mikyung Yu, Jun Wu, Jinjun Shi, Omid C. Farokhzad, Omid C. Farokhzad
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664315/
Nov 24, 2015 · The approval of the protein-drug conjugate Abraxane in 2005 gave further impetus to the field. Nanotherapeutics such as liposomes are based on a concept in which many copies of a drug molecule are loaded into a delivery vehicle (the NP) that is optimized for improved PK and PD relative to the drug by itself.Author: James R. Heath
https://www.sciencedirect.com/science/article/pii/S1773224717302514
In particular, biodegradable and biocompatible lipid and polymer-based nanocarriers have emerged as promising delivery platforms to enable the administration of proteins and peptides. This review provides an overview of the mostly explored nanotechnologies to date intended to produce lipidic and polymeric nanocarriers for protein/peptide delivery.Author: Irene Santalices, Andrea Gonella, Dolores Torres, María José Alonso
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949907/
Jul 16, 2007 · In drug delivery, nanotechnology is just beginning to make an impact. Many of the current “nano” drug delivery systems, however, are remnants of conventional drug delivery systems that happen to be in the nanometer range, such as liposomes, polymeric …Author: Kinam Park
https://www.researchgate.net/publication/317940267_Advances_on_the_formulation_of_proteins_using_nanotechnologies
Advances on the formulation of proteins using nanotechnologies Article in Journal of Drug Delivery Science and Technology · June 2017 with 142 Reads How we measure 'reads'
https://www.hindawi.com/journals/jdd/2011/181646/
The development of synthetic peptide-based vaccines has many advantages in comparison with vaccines based on live attenuated organisms, inactivated or killed organism, or toxins. Peptide-based vaccines cannot revert to a virulent form, allow a better conservation, and are produced more easily and safely. However, they generate a weaker immune response than other vaccines, and the inclusion of ...Author: Aiala Salvador, Aiala Salvador, Manoli Igartua, Manoli Igartua, Rosa María Salinas Hernández, Rosa M...
https://www.azonano.com/article.aspx?ArticleID=4668
Nov 01, 2017 · The application of nanotechnology for drug delivery provides the potential for enhanced treatments with targeted delivery and fewer side effects. Nanotechnology drug delivery applications occur through the use of designed nanomaterials as well as forming delivery systems from nanoscale molecules such as liposomes.
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