Nanoparticulate Systems For Polynucleotide Delivery

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Nanoparticulate systems for polynucleotide delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676661/
    These systems offer several advantages in terms of tissue penetrability, cellular uptake, systemic circulation, and cell targeting as compared to larger systems. They can protect the polynucleotide from a variety of degradative and destabilizing factors and enhance delivery efficiency to the cells.Author: Ashwin Basarkar, Jagdish Singh

(PDF) Nanoparticulate systems for polynucleotide delivery

    https://www.researchgate.net/publication/5826891_Nanoparticulate_systems_for_polynucleotide_delivery
    This article provides a review on the most commonly used nanoparticulate systems for gene delivery. We have discussed frequently used polymers, such as, polyethyleneimine, poly (lactide-co ...

Multifunctional, stimuli-sensitive nanoparticulate systems ...

    https://www.nature.com/articles/nrd4333
    Oct 07, 2014 · The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the in vivo effectiveness of drugs is now well established. The …Author: Vladimir P. Torchilin, Vladimir P. Torchilin

[Article Metrics] Nanoparticulate systems for ...

    https://www.dovepress.com/article_metric.php?article_id=693
    Dove Press is a member of the Open Access Initiative, specializing in peer reviewed Medical Journals. View articlesor submit your research for publishing

Low molecular weight chitosan nanoparticulate system at ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310411/
    Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery. Mohamad Alameh, Diogo DeJesus, ... P ratios are effective and nontoxic delivery systems for polynucleotide and siRNA delivery for in vitro gene silencing. Materials and methods. Synthesis of siRNAs and dsODNs.Author: Mohamad Alameh, Diogo DeJesus, Myriam Jean, Vincent Darras, Marc Thibault, Marc Lavertu, Michael D B...

(PDF) Low molecular weight chitosan nanoparticulate system ...

    https://www.researchgate.net/publication/223137304_Low_molecular_weight_chitosan_nanoparticulate_system_at_low_NP_ratio_for_nontoxic_polynucleotide_delivery
    Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery ... P ratio for nontoxic polynucleotide delivery.pdf ... Low molecular weight chitosan ...

NANOPARTICULATE DRUG DELIVERY SYSTEM - SlideShare

    https://www.slideshare.net/sagarsavale1/nanoparticulate-drug-delivery-system
    May 29, 2016 · NANOPARTICULATE DRUG DELIVERY SYSTEM ... Review on Nanoparticulate carriers Nanocarrier system Preparation method Polymer/ Lipid based system Drug Advantage/ Application Polymeric Solvent evaporation PEG with PEO coating Protein Fast drug release for 4 hours nanoparticles Solvent evaporation PLGA Dexamethasone Sustain release for 10 days ...

Jagdish Singh School of Pharmacy NDSU

    https://www.ndsu.edu/pharmacy/psci_people/jagdish_singh/
    Ashwin Basarkar and Jagdish Singh, Nanoparticulate systems for polynucleotide delivery. International Journal of Nanomedicine, 2, 353-360, 2007. Khaled Al-Tahami and Jagdish Singh, Smart polymer based delivery systems for peptides and proteins. Recent Patents on …

Low molecular weight chitosan nanoparticulate system at ...

    https://publications.polymtl.ca/3420/
    Chitosan, a natural polymer, is a promising system for the therapeutic delivery of both plasmid DNA and synthetic small interfering RNA. Reports attempting to identify the optimal parameters of chitosan for synthetic small interfering RNA delivery were inconclusive with high molecular weight at high amine-to-phosphate (N:P) ratios apparently required for efficient transfection.Author: Mohamad Alameh, Diogo DeJesus, Myriam Jean, Vincent Darras, Marc Thibault, Marc Lavertu, Michael D B...

Titre: Low molecular weight chitosan nanoparticulate ...

    https://publications.polymtl.ca/3420/1/2012_Merzouki_Low_molecular_weight_chitosan_nanoparticulate_ensemble.pdf
    delivery of the siRNA cargo. Moreover, we explore the physicochemical properties of these specific formulations with the prospect of optimizing nanoparticle transfection and silencing efficiencies. Our results demonstrate, for the first time, that LMW-CSs at low N:P ratios are effective and nontoxic delivery systems for polynucleotide and siRNA

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