We have collected information about Nanoparticulate Systems For Polynucleotide Delivery for you. Follow the links to find out details on Nanoparticulate Systems For Polynucleotide Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676661/
These systems offer several advantages in terms of tissue penetrability, cellular uptake, systemic circulation, and cell targeting as compared to larger systems. They can protect the polynucleotide from a variety of degradative and destabilizing factors and enhance delivery efficiency to the cells.Author: Ashwin Basarkar, Jagdish Singh
https://www.researchgate.net/publication/5826891_Nanoparticulate_systems_for_polynucleotide_delivery
This article provides a review on the most commonly used nanoparticulate systems for gene delivery. We have discussed frequently used polymers, such as, polyethyleneimine, poly (lactide-co ...
https://www.nature.com/articles/nrd4333
Oct 07, 2014 · The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the in vivo effectiveness of drugs is now well established. The …Author: Vladimir P. Torchilin, Vladimir P. Torchilin
https://www.dovepress.com/article_metric.php?article_id=693
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310411/
Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery. Mohamad Alameh, Diogo DeJesus, ... P ratios are effective and nontoxic delivery systems for polynucleotide and siRNA delivery for in vitro gene silencing. Materials and methods. Synthesis of siRNAs and dsODNs.Author: Mohamad Alameh, Diogo DeJesus, Myriam Jean, Vincent Darras, Marc Thibault, Marc Lavertu, Michael D B...
https://www.researchgate.net/publication/223137304_Low_molecular_weight_chitosan_nanoparticulate_system_at_low_NP_ratio_for_nontoxic_polynucleotide_delivery
Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery ... P ratio for nontoxic polynucleotide delivery.pdf ... Low molecular weight chitosan ...
https://www.slideshare.net/sagarsavale1/nanoparticulate-drug-delivery-system
May 29, 2016 · NANOPARTICULATE DRUG DELIVERY SYSTEM ... Review on Nanoparticulate carriers Nanocarrier system Preparation method Polymer/ Lipid based system Drug Advantage/ Application Polymeric Solvent evaporation PEG with PEO coating Protein Fast drug release for 4 hours nanoparticles Solvent evaporation PLGA Dexamethasone Sustain release for 10 days ...
https://www.ndsu.edu/pharmacy/psci_people/jagdish_singh/
Ashwin Basarkar and Jagdish Singh, Nanoparticulate systems for polynucleotide delivery. International Journal of Nanomedicine, 2, 353-360, 2007. Khaled Al-Tahami and Jagdish Singh, Smart polymer based delivery systems for peptides and proteins. Recent Patents on …
https://publications.polymtl.ca/3420/
Chitosan, a natural polymer, is a promising system for the therapeutic delivery of both plasmid DNA and synthetic small interfering RNA. Reports attempting to identify the optimal parameters of chitosan for synthetic small interfering RNA delivery were inconclusive with high molecular weight at high amine-to-phosphate (N:P) ratios apparently required for efficient transfection.Author: Mohamad Alameh, Diogo DeJesus, Myriam Jean, Vincent Darras, Marc Thibault, Marc Lavertu, Michael D B...
https://publications.polymtl.ca/3420/1/2012_Merzouki_Low_molecular_weight_chitosan_nanoparticulate_ensemble.pdf
delivery of the siRNA cargo. Moreover, we explore the physicochemical properties of these specific formulations with the prospect of optimizing nanoparticle transfection and silencing efficiencies. Our results demonstrate, for the first time, that LMW-CSs at low N:P ratios are effective and nontoxic delivery systems for polynucleotide and siRNA
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