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https://www.sciencedirect.com/science/article/pii/S0168365909005768
In addition, we explored the potential of nanoparticles formulated with propyl-starch derivatives for transdermal drug delivery. Both nanoparticle systems, PS-1 and PS-1.45, showed high encapsulation efficiency for a wide range of chemically different drugs. The drug release was driven by hydrophobic character of both the polymer and the drug.Author: M.J. Santander-Ortega, M.J. Santander-Ortega, T. Stauner, B. Loretz, J.L. Ortega-Vinuesa, D. Bastos-...
https://www.researchgate.net/publication/26760154_Nanoparticles_made_from_novel_starch_derivatives_for_transdermal_drug_delivery
Nanotechnology, in general, is making the most significant progresses in biomedical application, including novel drug delivery practices in which starch nanoparticles can be used as drug carriers.
https://www.sciencedirect.com/science/article/pii/S0144861711008277
Nanoparticles made from novel starch derivatives for transdermal drug delivery: Santander-Ortega et al. (2010) Propyl-starch nanoparticles were reported to show high encapsulation efficiency for three model drugs (flufenamic acid, testosterone and caffeine) intended for transdermal deliveryAuthor: Asha Rodrigues, Martins Emeje
https://www.sciencedirect.com/science/article/pii/B9780128167700000174
In different studies, modified carboxymethyl corn starch and hyperbranched 1,4-cis polybutadine (1,4-PBD) were used as novel polymer matrix for transdermal drug delivery of clonidine . The so-produced nanospheres showed a solid and consistent structure, with good spherical geometry, with a relatively broad particle size distribution (40–100 nm), and an average drug entrapment of 92.2% ± …Author: J. Marto, H.M. Ribeiro, A.J. Almeida
https://www.hindawi.com/journals/ijps/2014/340121/
This curcumin loading capacity was comparable to other drug carriers such as graphene oxide , which indicated that starch nanoparticles were indeed promising drug delivery carriers. Figure 8 Effect of curcumin concentration on loading capacity of curcumin onto starch nanoparticles.Author: Suk Fun Chin, Siti Nur Akmar Mohd Yazid, Suh Cem Pang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Nanoparticles are solid, colloidal particles consisting of macromolecular substances that vary in size from 10 nm to 1000 nm ( Kreuter, 1994a ). However, particles >200 nm are not heavily pursued and nanomedicine often refers to devices <200 nm (i.e., the width of microcapillaries).
https://www.sciencedirect.com/science/article/pii/S0014305713002243
In this article, a novel oral protein drug delivery made of starch nanoparticles (SNPs) as backbone and poly (l -glutamic acid) (PGA) as graft chains was successfully synthesized by click reaction. The grafting efficiency and structure of the resultant copolymer SNP- g -PGA …Author: Zhe Zhang, Hongling Shan, Li Chen, Chaoliang He, Xiuli Zhuang, Xuesi Chen
https://link.springer.com/chapter/10.1007/978-981-13-3657-7_3
Yet, the fast degradation of starch could be a hurdle in the application of starch in drug delivery systems (DDSs). Therefore, natural starches should be modified by physical, chemical, and enzymatic methods in order to expand the application of starch as drug carriers. Armed with the structural, physicochemical,...
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticles-for-dermal-and-transdermal-drug-delivery
The most used and investigated nanocarriers for dermal/transdermal drug delivery in the pharmaceutical field include liposomes, transfersomes, ethosomes, niosomes, dendrimers, nanoparticles-lipid and polymer nanoparticles, and nanoemulsions.Author: Okoro Uchechi, John D. N. Ogbonna, Anthony A. Attama
https://www.sciencedirect.com/science/article/pii/S0927776518305319
Starch nanoparticle applications in drug delivery systems are influenced by their particle size. This parameter can be regulated by their corresponding synthesis methods. Currently, most starch nanoparticles are prepared through emulsion cross-linking, solvent evaporation, precipitation, and supercritical fluid extraction [ 7 ].
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