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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693026/
Jun 18, 2013 · Ocular drug transport barriers pose a challenge for drug delivery comprising the ocular surface epithelium, the tear film and internal barriers of the blood-aqueous and blood-retina barriers. Ocular drug delivery efficiency depends on the barriers and the clearance from the choroidal, conjunctival vessels and lymphatic.Author: Hong-Yan Zhou, Ji-Long Hao, Shuang Wang, Yu Zheng, Wen-Song Zhang
https://www.sciencedirect.com/science/article/pii/S0142961217307755
In the past, several promising nanoparticles used for drug delivery have been put aside due to toxicity of the carrier , . The absence of toxicity is thus an important finding and allows for further development of the U4-12 nanocarriers as an ocular drug delivery platform.Author: Jan Willem de Vries, Sven Schnichels, José Hurst, Lisa Strudel, Agnieszka Gruszka, Minseok Kwak, Min...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870510/
The purpose of this study was to develop novel liquid crystalline nanoparticles (LCNPs) that display improved pre-ocular residence time and ocular bioavailability and that can be used as an ophthalmic delivery system for tetrandrine (TET).Author: Rui Liu, Shuangshuang Wang, Shiming Fang, Jialu Wang, Jingjing Chen, Xingguo Huang, Xin He, Changxia...
https://www.sciencedirect.com/science/article/pii/S0378517319309883
Dex-GCS nanoparticles showed acceptable ocular tolerance and provided a relatively longer precorneal retention compared with the aqueous solution formulation after topical administration, which might make Dex-GCS nanoparticle a promising candidate for ophthalmic drug delivery to treat various inflammatory disorders (e.g., uveitis). FundingAuthor: Ailing Yu, Hui Shi, Hui Liu, Zhishu Bao, Mali Dai, Dan Lin, Deqing Lin, Xu Xu, Xingyi Li, Yuqin Wang
https://www.researchgate.net/profile/Sudip_Das4/publication/279418971_Microparticles_and_Nanoparticles_in_Ocular_Drug_Delivery/links/5b8cd0e3299bf1d5a73a0ba4/Microparticles-and-Nanoparticles-in-Ocular-Drug-Delivery.pdf
ophthalmic drug delivery technique that may enhance dosage form accept- ability while providing sustained release in the ocular milieu (14). Particulate drug delivery consists of systems described ...
https://www.researchgate.net/publication/278696812_Nanotechnology_in_Ophthalmic_Drug_Delivery
The present chapter overviews the emerging role of nanotechnology in ophthalmic drug delivery with emphasis on what has been patented over the past decade. ... 438 of nanoparticles in ophthalmic ...
https://www.nature.com/articles/srep44229
Mar 14, 2017 · Drug delivery systems (DDSs) have been widely investigated to improve delivery of physiologically active agents to tumours 1,2,3,4,5,6, inflamed areas 7 …Author: Yoshikazu Ikuta, Shigenobu Aoyagi, Yuji Tanaka, Kota Sato, Satoshi Inada, Yoshitaka Koseki, Tsunenob...
http://www.eurekaselect.com/99717
Polymeric Nanoparticles for Ophthalmic Drug Delivery: An Update on Research and Patenting Activity Author(s): Sai H.S. Boddu . Department of Pharmacy Practice, The University of Toledo HSC, College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Ave. (MS1013), Toledo, OH 43614, USA.Author: Sai H.S. Boddu
https://nanoscalereslett.springeropen.com/articles/10.1186/s11671-016-1471-0
May 17, 2016 · The purpose of this study was to develop novel liquid crystalline nanoparticles (LCNPs) that display improved pre-ocular residence time and ocular bioavailability and that can be used as an ophthalmic delivery system for tetrandrine (TET). The delivery system consisted of three primary components, including glyceryl monoolein, poloxamer 407, and water, and two secondary …Author: Rui Liu, Shuangshuang Wang, Shiming Fang, Jialu Wang, Jingjing Chen, Xingguo Huang, Xin He, Changxia...
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2010.483257
Solid lipid nanoparticles for ocular drug delivery Ali Seyfoddin, John Shaw, and Raida Al-Kassas University of Auckland, Faculty of Medical and Health Sciences, School of Pharmacy, Auckland, New Zealand Abstract Ocular drug delivery remains challenging because …
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