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https://www.horiba.com/fileadmin/uploads/Scientific/Documents/PSA/Webinar_Slides/AP028.pdf
PLA Nanoparticles for Drug Delivery Targeting ligand provides recognition, enabling targeted nanoparticles to identify and bind to their intended target site. Surface functionalization shields targeted nanoparticles from the immune system. Polymer matrix encapsulates payload molecules in a matrix of biodegradable polymers . Therapeutic payloads include
http://www.nanoparticles.org/pdf/Pun.pdf
Examples of Nanoparticles for Drug Delivery DOXIL Formulation 1. Doxorubicin-containing core 2. Lipid Bilayer membrane 3. PEG-coated surface 4. <100 nm Examples of Nanoparticles for Drug Delivery DOXIL Proposed Mechanism of Action Examples of Nanoparticles for Drug Delivery DOXIL Pharmacokinetics Rats Dogs Gabizon, et al. Pharm Res v10:703 (1993)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
So, for drug delivery biodegradable nanoparticle formulations are needed as it is the intention to transport and release the drug in order to be effective. However, model studies to the behavior of nanoparticles have largely been conducted with non-degradable particles.Author: Wim H De Jong, Paul Ja Borm
https://www.powershow.com/viewht/7aa0f-ZDc1Z/Nanotechnology_Based_Drug_Delivery_powerpoint_ppt_presentation
The Use of Nanoparticles in Drug Delivery Systems - Doxil is the drug doxorubicin HCl encapsulated in an antibody linked PEGylated liposome ...
http://www.authorstream.com/Presentation/aSGuest115913-1207997-nanoparticles-in-drug-delivery/
Sep 30, 2011 · role of nanoparticles in drug delivery- authorSTREAM Presentation. TARGETED DRUG DELIVERY: Delivering a drug to a specific site in the body where it has the greatest effect, instead of allowing it to diffuse to various sites, where it may cause damage or trigger side effects.
https://www.sciencedirect.com/science/article/pii/B9780444626141000077
Although chemical and physical enhancers have been developed, they need high doses or high potency to exert efficiency, which induces irritation, causes damage, and reduces the skin barrier function. Consequently, a nanoparticle delivery system is gaining increased attention as a transdermal drug delivery carrier.Author: Keishiro Tomoda, Kimiko Makino
https://www.slideshare.net/patelbindi/nanoparticle-37752067
Aug 07, 2014 · INTRODUCTION » DEFINITION: » Nanoparticles are subnanosized colloidal drug delivery systems » particle size ranges from 10-1000 nm in diameter. » They are composed of synthetic or semi synthetic polymers carrying drugs or proteinaceous substances, i.e. antigen (s).
https://www.slideshare.net/sagarsavale1/nanoparticulate-drug-delivery-system
May 29, 2016 · 5) Targeted drug delivery. This system has showed tremendous potential in target drug delivery, especially to brain. Successful targeting of peptide Dalargin to brain by employing surface modified poly (isobutyl cyanoacrylate) Nanoparticle has been the major achievement in target drug delivery. Natural targeting of RES by nanosuspension has been already described.
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