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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449975/
Apr 28, 2017 · 1. Introduction. Nanotechnology has seen many advances in recent years, both in terms of the development of novel materials, often with tunable properties [1,2] and applications in a growing number of areas.An area of particular interest, and the topic of this review, is gene therapy.Author: Michael K. Riley, Wilfred Vermerris
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046008/
May 21, 2014 · Nanoparticles in gene delivery. In the field of nanomedicine, nanotechnology methods focus on formulating therapeutic biocompatible agents such as nanoparticles, nanocapsules, micellar systems, and conjugates [22,23].Nanoparticles are solid and spherical structures ranging to around 100 nm in size and prepared from natural or synthetic polymers [].Author: Solmaz Maleki Dizaj, Samira Jafari, Ahmad Yari Khosroushahi
https://www.researchgate.net/publication/259488402_A_Mini_Review_of_Biodegradable_Calcium_Phosphate_Nanoparticles_For_Gene_Delivery
In this review, we focus on the current research activity in the development of calcium phosphate nanoparticlss for gene delivery. Calcium phosphate nanoparticles are mainly classified into lipid ...
https://www.sciencedirect.com/science/article/pii/S0168365913008079
Overall, its biodegradability, biocompatibility, chemical modification potential and cross-linking possibility make gelatin-based nanoparticles (GNPs) a promising carrier system for drug delivery. This review paper will focus on GNPs used as vectors for drug and gene delivery.Author: Ahmed O. Elzoghby
https://www.researchgate.net/publication/305655393_Nanoparticles_in_Gene_Therapy
Nanoparticles in Gene Therapy. ... A major approach discussed is the use of Nanoparticles as non-viral carriers for gene delivery purposes regarding their favorable characteristics such as their ...
https://www.sciencedirect.com/science/article/pii/S2352407318300313
Surface modified silica nanoparticles were potentially useful as gene delivery carriers because of their inert nature, large surface area and cationic charge distribution that helps in conjugation with target molecules (Kneuer et al., 2000). Silica, the second most abundant element on earth, is …Author: Indrani Manna, Maumita Bandyopadhyay
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(16)30165-6
Jan 01, 2016 · Nanoparticles have been proved to be the most promising vehicles for clinical gene therapy due to their tunable size, shape, surface, and biological behaviors. In this review, the clinical development of nanoparticles for gene delivery will be particularly highlighted.Author: Jie Chen, Zhaopei Guo, Huayu Tian, Xuesi Chen
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1872-2113&volume=3&issue=2&spage=125
Keywords:Gene delivery, nanoparticles, nanoparticles modification, gene transfection efficiency. Abstract: Gene therapy, as therapeutic treatment to genetic or acquired diseases, is attracting much interest in the research community, leading to noteworthy developments over the past two decades. Nonviral vectors have recently received an ...
https://www.nature.com/articles/s41570-018-0039-1
Sep 21, 2018 · In this Review, the authors discuss the latest developments in synthetic materials used for gene delivery and the challenges that must be overcome to transfer these innovations into the clinic.Author: Irene Lostalé-Seijo, Javier Montenegro
https://www.liebertpub.com/doi/10.1089/jop.2012.0128
The present review summarizes scientific results that evidence the potential application of lipid nanoparticles as drug delivery systems for the retina and also as nonviral vectors in gene therapy of retina disorders, although much more effort is still needed before these …Author: Ana del Pozo-Rodríguez, Diego Delgado, Alicia R. Gascón, Maria Ángeles Solinís
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