Nanoparticles For Intracellular-Targeted Drug Delivery

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(PDF) Nanoparticles for intracellular-targeted drug delivery

    https://www.researchgate.net/publication/51815471_Nanoparticles_for_intracellular-targeted_drug_delivery
    Nanoparticles for intracellular-targeted drug delivery Article · Literature Review (PDF Available) in Nanotechnology 22(49):494002 · December 2011 with 1,054 Reads How we measure 'reads'

Targeted Drug Delivery with Nanoparticles

    https://courses.helsinki.fi/sites/default/files/course-material/4523810/BJK%20nano%20241017.pdf
    nanoparticles –Oral targeted drug delivery requires small molecular ... Intracellular targeted delivery is requirement Targeted delivery to the 1) extracellular space in target tissue drug release locally 2) into the target cells in the tissue . Drug Targeting with Nanosystems X.

Doxorubicin-Tethered Responsive Gold Nanoparticles ...

    https://pubs.acs.org/doi/abs/10.1021/nn200007z
    Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications. Molecules 2017, 22 (9) , 1445. DOI: 10.3390/molecules22091445. Tianying Zheng, Aijun Wang, Dongyan Hu, Yonggang Wang. Tumor-targeting templated silica nanoparticles as a dual-drug delivery system for anti-angiogenic ovarian cancer therapy. ...

Strategies in the design of gold nanoparticles for ...

    https://www.future-science.com/doi/10.4155/tde-2017-0049
    With unique physicochemical properties, gold nanoparticles (Au NPs) have demonstrated their potential as drug carriers or therapeutic agents. Effective guidance of Au NPs into specific intracellular destinations becomes increasingly important as we strive to further improve the efficiency of drug delivery and modulate controllable cellular responses.

Targeted Charge‐Reversal Nanoparticles for Nuclear Drug ...

    https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.200605254
    John W Rasmussen, Ezequiel Martinez, Panagiota Louka and Denise G Wingett, Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications, Expert Opinion on Drug Delivery, 10.1517/17425247.2010.502560, 7, 9, (1063-1077), (2010).

A smart multifunctional nanocomposite for intracellular ...

    https://www.researchgate.net/publication/51634838_A_smart_multifunctional_nanocomposite_for_intracellular_targeted_drug_delivery_and_self-release
    A smart multifunctional nanocomposite for intracellular targeted drug delivery and self-release Article (PDF Available) in Nanotechnology 22(41):415101 · September 2011 with 87 Reads

Development of nanomaterials for bone-targeted drug delivery

    https://www.sciencedirect.com/science/article/pii/S1359644617302404
    Furthermore, the intracellular targeting drug delivery based on nanotechnology can enhance the treatment efficiency of bone diseases via the precise delivery of drugs to subcellular regions. As a result, intracellular targeted delivery shows great potential to solve multidrug resistance, a longstanding challenge for cancer chemotherapy 30, 31 ...

Targeted Drug Delivery Systems: Strategies and Challenges ...

    https://link.springer.com/chapter/10.1007%2F978-3-319-11355-5_1
    The task of selecting a targeted drug delivery approach is intricate and depends on the therapeutic substance, the disease as well as the specific location of the disease. This chapter aims to provide an overview of the challenges and the strategies employed in targeted drug delivery.

Development Of Targeting Nanoparticles Mimicking The ...

    https://rc.library.uta.edu/uta-ir/handle/10106/10
    The development of biodegradable nanoparticles as drug delivery vehicles presents an improved avenue for intracellular targeted drug delivery. Biodegradable nanoparticles have demonstrated an ability to provide controllable, sustained drug release in vitro. However, in vivo studies have shown that nanoparticles are not effective at adhering to ...

N-Doped graphene quantum dot@mesoporous ... - SpringerLink

    https://link.springer.com/article/10.1007/s00604-017-2598-0
    Dec 18, 2017 · The authors describe new bifunctional mesoporous silica nanoparticles (NPs) for specific targeting of tumor cells and for intracellular delivery of the cancer drug doxorubicin (DOX). Mesoporous silica nanoparticles (MSNPs) were coated with blue fluorescent N-graphene quantum dots, loaded with the drug DOX, and finally coated with hyaluronic acid (HA). Cellular uptake of the NPs with an ...

Research Paper Homing in on an intracellular target for ...

    http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=20021&path%5B%5D=63877
    agents for targeted delivery. In this case, we plan to use ligands of HDACs to decorate the PLGA nanoparticle for intracellular targeted delivery. What is also unique in this study is the targeting of an intracellular component, HDACs, instead of a cell surface biomarker. The search for intracellular drug delivery …

Hyaluronic acid-coated chitosan nanoparticles induce ROS ...

    https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-016-0245-2
    Jan 10, 2017 · Owing to its ability to specifically target CD44 receptors, HA has been frequently modified with a drug carrier to enhance drug delivery in CD44-overexpressed tumor cells to effectively inhibit tumor growth [10–15]. Nanoparticles (NPs), an effective drug delivery system, have shown potential clinical application in the treatment of cancer.

Intracellular targeted co-delivery of shMDR1 and gefitinib ...

    https://www.dovepress.com/intracellular-targeted-co-delivery-of-shmdr1-and-gefitinib-with-chitos-peer-reviewed-article-IJN
    Jul 15, 2015 · The main aims of this research were to design a nanodelivery system for accomplishing the effective co-delivery of gene and antitumor drug and overcoming multidrug resistance effect. In this study, shMDR1 and gefitinib-encapsulating chitosan nanoparticles with sustained release, small particle size, and high encapsulation efficiency were prepared.

A novel acemannan-chitosan modified lipid nanoparticles as ...

    https://japsonline.com/admin/php/uploads/2778_pdf.pdf
    nanocarriers for intracellular-targeted delivery. Over the decades, nanoparticles including polymeric nanoparticles, liposomes, dendrimers, nanostructured lipid carrier (NLC), and polymeric micelles have been explored for intracellular delivery of antimicrobial drugs that demonstrate a high bactericidal activity in vitro. Nanoparticles have been

Getting a Handle on Smart Drug Delivery Systems – A ...

    https://www.intechopen.com/books/smart-drug-delivery-system/getting-a-handle-on-smart-drug-delivery-systems-a-comprehensive-view-of-therapeutic-targeting-strate
    Smart drug delivery system (SDDS) is a recently emerging therapeutic approach, now turning into a conventional model to deliver drug to specific sites or target. Drug targeted (DT) delivery systems maintain the concentration of the drugs at desirable doses in the body and avoid the need for repeated doses. The DT delivery system have specific distinguishing features such as self-regulated, pre ...

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