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https://www.researchgate.net/publication/258390711_Nanoparticles_for_Brain_Drug_Delivery
As a consequence, several strategies are currently being sought after to enhance the delivery of drugs across the BBB. Within this review, the recently born strategy of brain drug delivery based on...
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
Nanoparticles for drug delivery to the brain is a method for transporting drug molecules across the blood–brain barrier (BBB) using nanoparticles.These drugs cross the BBB and deliver pharmaceuticals to the brain for therapeutic treatment of neurological disorders.
https://www.hopkinsmedicine.org/news/media/releases/improved_nanoparticles_deliver_drugs_into_brain
Sep 11, 2012 · The brain is a notoriously difficult organ to treat, but Johns Hopkins researchers report they are one step closer to having a drug-delivery system flexible enough to overcome some key challenges posed by brain cancer and perhaps other maladies affecting that organ.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306759/
Nov 27, 2018 · The use of nanoparticles to diagnose brain diseases or to assist the delivery of drugs across the blood brain barrier has gained a great interest, since they offer a series of advantages, namely targeting efficiency, non-invasiveness, biodegradability, stability, and controllability to load and release drugs .
https://www.tandfonline.com/doi/abs/10.1081/DDC-120001481
Nanoparticles (NP) are solid colloidal particles ranging in size from 1 to 1000 nm that are utilized as drug delivery agents. The use of NPs to deliver drugs to the brain across the blood-brain barrier (BBB) may provide a significant advantage to current strategies.
http://downloads.hindawi.com/archive/2013/238428.pdf
cantly precludes the delivery of drugs to the brain, thus, preventing the therapy of a number of neurological disorders. As a consequence, several strategies are currently being sought a er to enhance the delivery of drugs across the BBB. Within this review, the recently born strategy of brain drug delivery based on the use of nanoparticles,
https://medcraveonline.com/JAPLR/peptide-encapsulated-nanoparticles-for-brain-drug-delivery.html
Oct 29, 2016 · The blood-brain barrier (BBB) is performing as a shielding barrier which is designed to protect the environment in the brain. It prevents the entry of dangerous substances into the brain but hinder the administration of some drugs to treat brain and central nervous system. Recently nanoparticles are playing a major role in targeted drug delivery.
http://www.eurekaselect.com/123425/article
The delivery of drugs to the brain via the nose-to-brain route holds great promise, on the basis of preclinical research by means of drug delivery systems such as polymeric nanoparticles and clinical data related to intranasal delivery to CNS of large molecular weight biologics administered in solution, but safety issues about toxicity on nasal ...
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
27 Chertok et al., Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors, Biomaterials, Volume 29, Issue 4, February 2008 28 Songa et al., Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery, Journal of
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978509/
Nanoparticle-based drug delivery platforms have emerged as suitable vehicles for overcoming pharmacokinetic limitations associated with conventional drug formulations. Nanoparticles, such as liposomes, have proven advantageous at solubilizing therapeutic cargos, substantially prolonging the circulation lifetimes of drugs 2.
https://phys.org/news/2020-04-tiny-nanoparticles-large-potential-brain.html
2 days ago · The nanoparticles gain entry to the brain because they've been engineered to look like amino acids, ... 'Sticky' particles promise more precise drug delivery for brain cancer. May 22, 2017.
https://www.future-science.com/doi/pdfplus/10.4155/tde.15.56
nanoparticles to pass from the brain endo-thelial cells and further into the brain are Targeted drug delivery to the brain using magnetic nanoparticles Louiza Bohn Thomsen*,1, Maj Schneider Thomsen1 & Torben Moos1 1Laboratory of Neurobiology, Section of Biomedicine, Department of Health Science & Technology, Aalborg
https://newatlas.com/medical/nanoparticles-blood-brain-barrier-cancer/
3 days ago · “But this finding suggests a new direction for developing nanoparticles for drug delivery to the brain by targeting LAT1 molecules.” The research was published in the journal Nature Biomedical ...
https://medicine.yale.edu/neurosurgery/news-article/23744/
3 days ago · As a result, chemotherapy drugs can be loaded on the dots and target tumors while barely affecting the rest of the body. The nanoparticles gain entry to the brain because they’ve been engineered to look like amino acids, which are allowed past the blood-brain barrier as nutrients. The nanoparticles have wider implications than drug delivery.
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