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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306759/
Nov 27, 2018 · The use of nanoparticles to diagnose brain diseases or to assist the delivery of drugs across the blood brain barrier has gained a great interest, since they offer a series of advantages, namely targeting efficiency, non-invasiveness, biodegradability, stability, and controllability to …Author: Daniel Mihai Teleanu, Cristina Chircov, Alexandru Mihai Grumezescu, Adrian Volceanov, Raluca Ioana T...
https://www.hindawi.com/journals/isrn/2013/238428/
As a consequence, several strategies are currently being sought after to enhance the delivery of drugs across the BBB. Within this review, the recently born strategy of brain drug delivery based on the use of nanoparticles, multifunctional drug delivery systems with size in …Author: Massimo Masserini
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Uptake and effects of nanoparticles in the brain . Nanoparticles can get access to the brain by two different mechanisms, ie, (1) transsynaptic transport after inhalation through the olfactory epithelium, and (2) uptake through the blood-brain barrier.Author: Wim H De Jong, Paul Ja Borm
https://www.sciencedirect.com/science/article/pii/S0168365916303236
Blood–brain barrier (BBB) transport mechanisms for brain delivery of nanoparticles (NPs). The BBB is highly selective and has specific transport mechanisms allowing a close control of molecules/cells that enter the brain parenchyma.Author: Cláudia Saraiva, Catarina Praça, Raquel Ferreira, Tiago Santos, Lino Ferreira, Liliana Bernardino
https://www.sciencedirect.com/science/article/pii/S2211383516301186
Several barriers are faced in brain-targeted delivery. To overcome these barriers and deliver drugs and imaging probes to the brain, various strategies have been developed for overcoming the blood–brain barrier (BBB), directly targeting diseased brain cells, and dual targeting delivery.Author: Huile Gao
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