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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853888/
These colloidal particulate systems with size ranging from 10 nm to 1000 nm offer targeted drug delivery, sustained release, protection of labile groups from degradation, low toxicity and drug adhesivity to the skin. Drug-release nanocarriers, such as liposomes, micelles, polymeric and solid lipid nanoparticles as well as inorganic nanoparticles and sub-micrometric emulsions are now available.
https://www.sciencedirect.com/science/article/abs/pii/S0169409X11000160
Skin is a widely used route of delivery for local and systemic drugs and is potentially a route for their delivery as nanoparticles. The skin provides a natural physical barrier against particle penetration, but there are opportunities to deliver therapeutic nanoparticles, especially in diseased skin and to the openings of hair follicles.Author: Tarl W. Prow, Jeffrey E. Grice, Lynlee L. Lin, Rokhaya Faye, Margaret Butler, Wolfgang Becker, Elisa...
https://www.sciencedirect.com/science/article/pii/S0169409X11000160
As stated in the SCCP nanotechnology report , there is limited data on skin penetration of nanoparticles through diseased skin. Topical nanoparticle drug delivery for local effects is likely to be used on diseased skin. Among the most common adult skin diseases are atopic dermatitis (6.9%) and psoriasis (6.6%) . The effects of these barrier altering diseases on the penetration of nanoparticles …Author: Tarl W. Prow, Jeffrey E. Grice, Lynlee L. Lin, Rokhaya Faye, Margaret Butler, Wolfgang Becker, Elisa...
https://www.researchgate.net/publication/49830276_Nanoparticles_and_microparticles_for_skin_drug_delivery
Topical nanoparticle drug delivery takes place in three major sites: stratum corneum (SC) surface (panel a), furrows (dermatoglyphs) (panel b), and openings of hair follicles (infundibulum) (c). The nanoparticles are shown in green and the drug in red. Other sites for delivery …
https://www.hindawi.com/journals/bmri/2014/895986/
4. Drug Delivery Nanoparticles in Nonmelanoma Skin Cancers: Squamous and Basal Cell Carcinomas. Among the three main types of skin cancer: melanoma, basal cell carcinoma (BCC), and squamous cell carcinoma (SCC), BCC is the most common form, …Author: Chiara Dianzani, Gian Paolo Zara, Giovanni Maina, Piergiorgio Pettazzoni, Stefania Pizzimenti, Feder...
http://sustainable-nano.com/2016/09/21/dermal-drug-delivery/
Sep 21, 2016 · Nanoparticles can provide solutions to some challenges with dermal drug delivery (image adapted from Richard Drdul) One important characteristic is amphipathic behavior. Scientists design particles with both a polar (water-loving) region and a nonpolar (fat-loving) region.
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-019-0514-y
Jul 10, 2019 · Nano-drug delivery system in wound treatment and skin regeneration Nano-DDSs hold immense potential in enhancement of drug therapeutic efficacy for their capability of preventing drug degradation and sustaining drug release.Author: Wei Wang, Kong-jun Lu, Chao-heng Yu, Qiao-ling Huang, Yong-Zhong Du
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835875/
Jul 10, 2009 · Drug delivery as well as risk assessment depends crucially on the ability of such carriers to overcome the skin barrier and reach deeper tissue layers. Therefore, the interaction of nanoparticles with skin and especially skin models is an intriguing field. However, the data obtained do not show a clear image on the effect of nano-carriers.
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