Nasal Delivery Systemic

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Tailoring Formulations for Intranasal Nose-to-Brain ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161189/
    Aug 03, 2018 · Therefore, some devices were developed to enable N2B drug delivery. Devices as the electronic atomizer ViaNase TM or the bidirectional breath-powered nasal delivery device called OptiMist TM that both, deliver drugs to a larger surface of the nasal cavity than pump sprays and droppers do. The OptiMistâ„¢ device consists of a mouthpiece and a ...Author: Stella Gänger, Katharina Schindowski

Nasal drug delivery devices: characteristics and ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
    Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland

Nasal Drug Delivery - Contract Pharma

    https://www.contractpharma.com/issues/2019-01-01/view_features/nasal-drug-delivery
    One of the benefits of nasal delivery for systemic drugs is that they can bypass the blood-brain barrier and enter the brain directly via the olfactory and trigeminal nerve pathways. 2-4 Additionally, the nasal cavity has a thin, well vascularised mucosa. 5 Drug molecules can transfer across this layer directly to the systemic blood circulation ...

(PDF) Nasal drug delivery system - an overview

    https://www.researchgate.net/publication/49601002_Nasal_drug_delivery_system_-_an_overview
    Due to the high permeability, high vasculature, low enzymatic environment of nasal cavity and avoidance of hepatic first pass metabolism are well suitable for systemic delivery of drug molecule ...

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