Nanoparticle Strategies For The Oral Delivery Of Insulin

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Nanoparticle strategies for the oral delivery of insulin.

    https://www.ncbi.nlm.nih.gov/pubmed/18095928
    Since its discovery, insulin remains the major treatment for Type 1 diabetes and many Type 2 diabetic patients, with insulin being administered parenterally. The oral route of insulin delivery, being the most comfortable, would also be the most physiologically advantageous in taking advantage of the portal-hepatic route of absorption.Author: Christiane Damgé, Catarina Pinto Reis, Philippe Maincent

(PDF) Nanoparticle strategies for the oral delivery of insulin

    https://www.researchgate.net/publication/5753004_Nanoparticle_strategies_for_the_oral_delivery_of_insulin
    Nanoparticle strategies for the oral delivery of insulin Article · Literature Review (PDF Available) in Expert Opinion on Drug Delivery 5(1):45-68 · February 2008 with 1,174 Reads

Nanoparticle strategies for the oral delivery of insulin

    https://www.researchgate.net/profile/Catarina_Reis/publication/5753004_Nanoparticle_strategies_for_the_oral_delivery_of_insulin/links/55954af508ae99aa62c6daa1/Nanoparticle-strategies-for-the-oral-delivery-of-insulin.pdf
    Nanoparticle strategies for the oral delivery of insulin 2 Expert Opin. Drug Deliv. (2008) 5(1) to have been the dream since the discovery of insulin.

Nanoparticle based insulin delivery system: the next ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619439/
    Oct 24, 2015 · At this juncture, researchers are trying to develop different insulin delivery systems, especially through oral and pulmonary route using nanocarrier based delivery system. This next generation efficient therapy for T1DM may help to improve the quality of life of diabetic patients who routinely employ insulin by the subcutaneous route.Author: Garima Sharma, Garima Sharma, Ashish Ranjan Sharma, Ju-Suk Nam, George Priya C. Doss, Sang-Soo Lee, ...

Nanoparticle strategies for the oral delivery of insulin ...

    https://www.tandfonline.com/doi/abs/10.1517/17425247.5.1.45
    Since its discovery, insulin remains the major treatment for Type 1 diabetes and many Type 2 diabetic patients, with insulin being administered parenterally. The oral route of insulin delivery, being the most comfortable, would also be the most physiologically advantageous in taking advantage of the portal–hepatic route of absorption. However, insulin is less absorbed by the intestinal ...Author: Christiane Damgé, Catarina Pinto Reis, Philippe Maincent

Potential of insulin nanoparticle formulations for oral ...

    https://www.sciencedirect.com/science/article/pii/S0168365917308283
    4. Barriers to oral delivery of insulin nanoparticle formulation. Effective oral delivery of insulin remains a significant challenge due to a few physiological barriers. The major barriers to oral administration of insulin can be classified as physical, chemical and enzymatic.Author: Chun Y. Wong, Hani Al-Salami, Crispin R. Dass

Polymer-based nanoparticles for oral insulin delivery ...

    https://www.sciencedirect.com/science/article/pii/S073497501500035X
    Polymer-based nanoparticles for oral insulin delivery: Revisited approaches ... other companies trying their efforts to achieve a good polymer-based nanoparticle system for the oral delivery of insulin such as Aphios Corp. (Woburn, MA, USA) and NOD Pharmaceuticals, Inc. (San Diego, CA, USA), however the information about the used polymers and ...Author: Pedro Fonte, Francisca Araújo, Cátia Silva, Carla Pereira, Salette Reis, Hélder A. Santos, Bruno Sar...

Oral insulin delivery: existing barriers and current ...

    https://www.onlinelibrary.wiley.com/doi/full/10.1111/jphp.12852
    Nov 28, 2017 · This review summarizes the rationale for oral insulin administration, existing barriers and some counter‐strategies trialled. Key findings. Oral insulin mimics the physiology of endogenous insulin secreted by pancreas. Following the intestinal absorption of oral insulin, it reaches the liver at high concentration via the portal vein.Author: Ahmed Gedawy, Jorge Martinez, Hani Al‐Salami, Crispin R. Dass

Nanoparticle Insulin Drug Delivery — Applications and New ...

    https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticle-insulin-drug-delivery-applications-and-new-aspects
    Nanoparticle Insulin Drug Delivery — Applications and New Aspects. ... In order to overcome the problems associated with parenteral administration of insulin several strategies that are based on nanotechnology has been developed to enhance the intestinal absorption of different protein and peptides. ... Oral insulin delivery with SLNs ...Author: Hatice Kübra Elçioğlu, Ali Demir Sezer

Oral Bioavailability of Insulin Contained in ...

    https://pubs.acs.org/doi/full/10.1021/bm0703923
    Nanoparticle strategies for the oral delivery of insulin. Expert Opinion on Drug Delivery 2008, 5 (1) , 45-68. DOI: 10.1517/17425247.5.1.45. Christiane Damgé, Catarina Pinto Reis, Philippe Maincent. Nanoparticle strategies for the oral delivery of insulin.Author: Bruno Sarmento, António Ribeiro, Francisco Veiga, Domingos Ferreira, Ronald Neufeld

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