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https://aiche.onlinelibrary.wiley.com/doi/full/10.1021/bp060348j
The scope of the rapid progress in nanomedicine ranges from in vivo imaging and diagnosis to therapeutics such as drug delivery and gene therapy. One of the most attractive applications of nanotechnology is its ability to significantly improve the sensitivity of biosensors. ... siRNA Delivery Using Nanoparticles. Gene silencing mediated by ...Author: Sha Jin, Kaiming Ye
https://onlinelibrary.wiley.com/doi/abs/10.1021/bp060348j
The ability to incorporate drugs or genes into a functionalized nanoparticle demonstrates a new era in pharmacotherapy for delivering drugs or genes selectively to tissues or cells.Author: Sha Jin, Kaiming Ye
http://onlinelibrary.wiley.com/doi/10.1021/bp060348j/references
Biomedical application of nanotechnology is a rapidly developing area that raises new prospect in the improvement of diagnosis and treatment of human diseases. The ability to incoAuthor: Sha Jin, Kaiming Ye
https://www.researchgate.net/publication/6534362_Nanoparticle-Mediated_Drug_Delivery_and_Gene_Therapy
The ability to incorporate drugs or genes into a functionalized nanoparticle demonstrates a new era in pharmacotherapy for delivering drugs or genes selectively to tissues or cells.
https://www.researchgate.net/publication/26259469_Nanoparticle-Mediated_Gene_Delivery
Nanoparticle-Mediated Drug Delivery and Gene Therapy Sha Jin † and Kaiming Ye* ,‡ DNA Resource Center and Biomedical Engineering Program, College of Engineering, University of Arkansas,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783414/
Multidrug resistance (MDR) remains a major barrier to the success of anticancer chemotherapy [1]. MDR is often mediated by drug efflux transporters such as P-glycoprotein (P-gp), which are overexpressed in cancer cells [2].Author: Yogesh B. Patil, Suresh Kumar Swaminathan, Tanmoy Sadhukha, Linan Ma, Jayanth Panyam
https://www.sciencedirect.com/science/article/pii/S016836591100575X
Dec 10, 2011 · Nanoparticle mediated delivery of pure P53 supercoiled plasmid DNA for gene therapy Author links open overlay panel Vítor M. Gaspar a Ilídio J. Correia a Ângela Sousa a Filomena Silva a Catarina M. Paquete b João A. Queiroz a Fani Sousa aAuthor: Vítor Manuel Abreu Gaspar, Ilídio Correia, Ângela Maria Almeida de Sousa, Filomena Silva, Catarina P...
https://www.nature.com/articles/am2017185
Oct 27, 2017 · However, the expanding applications of the CRISPR/Cas9 system are limited by its large size, especially in the widely used Cas9 derived from Streptococcus pyogenes. Although viral vectors show excellent gene transfection efficiency, they may result in off-target modification of the gene, mutagenesis and carcinogenesis.Author: Lingmin Zhang, Lingmin Zhang, Peng Wang, Qiang Feng, Nuoxin Wang, Zitian Chen, Yanyi Huang, Wenfu Zh...
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(16)30165-6
Jan 01, 2016 · Nanoparticles have been proved to be the most promising vehicles for clinical gene therapy due to their tunable size, shape, surface, and biological behaviors. In this review, the clinical development of nanoparticles for gene delivery will be particularly highlighted.Author: Jie Chen, Zhaopei Guo, Huayu Tian, Xuesi Chen
https://www.nature.com/articles/s41565-020-0669-6?error=cookies_not_supported&code=77395623-c20b-4a56-a39c-72d2c8d16cc2
The addition of selective organ targeting molecules to nanoparticles allows the specific targeting of extrahepatic tissues, enabling gene editing of distinct cell populations outside the liver.
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