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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The aims for nanoparticle entrapment of drugs are either enhanced delivery to, or uptake by, target cells and/or a reduction in the toxicity of the free drug to non-target organs. Both situations will result in an increase of therapeutic index, the margin between the doses resulting in a therapeutic efficacy (eg,...Author: Wim H De Jong, Paul Ja Borm
https://www.tandfonline.com/doi/full/10.1080/10717544.2018.1477857
Jun 05, 2018 · In the past 40 years, the nanoparticle drug delivery system for tumor peptide vaccines has been widely studied which also reached a splendid result. Nanomaterial can enhance the targeting of vaccines, help vaccines enter the cells and trigger immune response by themselves.Author: Jiemin Wang, Xiongbin Hu, Daxiong Xiang
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES Considerable research and development is devoted to improving drug delivery through the use of nanoparticles.
https://www.sciencedirect.com/science/article/abs/pii/S1734114012709015
Abstract. Controlled drug delivery systems (DDS) have several advantages compared to the traditional forms of drugs. A drug is transported to the place of action, hence, its influence on vital tissues and undesirable side effects can be minimized. Accumulation of therapeutic compounds in the target site increases and, consequently,...Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://www.sciencedirect.com/science/article/pii/S1734114012709015
Nanocarriers used in drug delivery system. According to the definition from NNI (National Nanotechnology Initiative), nanoparticles are structures of sizes ranging from 1 to 100 nm in at least one dimension. However, the prefix “nano” is commonly used for particles that are up to several hundred nanometers in size.Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://www.scholars.northwestern.edu/en/publications/drug-loaded-nanoparticle-systems-and-adult-stem-cells-a-potential
Nanoparticle-loaded delivery systems have recently arisen as an exciting alternative to improve targeted anti-glioma drug delivery. As drug carriers, they are able to efficiently protect the therapeutic agent and allow for sustained drug release. In addition, their surface can be easily manipulated with the addition of special ligands,which are ...Author: Brenda Auffinger, Ramin Morshed, Alex Tobias, Yu Cheng, Atique U Ahmed, Maciej S Lesniak
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Nanoparticle Delivery Systems Nanocapsules are vesicular systems in which a drug is confined to a cavity surrounded by a polymer membrane, whereas nanospheres are matrix systems in which the drug is physically and uniformly dispersed.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://en.wikipedia.org/wiki/Nanoparticle
The optimum composition reported by these researchers is 30% w/w of SiO 2 (~ 12 nm) in dye-doped PMMA.Nanoparticles are being investigated as potential drug delivery system. Drugs, growth factors or other biomolecules can be conjugated to nano particles to aid targeted delivery. [114]
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