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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Nanoparticle Delivery Systems. Nanocapsules are vesicular systems in which a drug is confined to a cavity surrounded by a polymer membrane, whereas nanospheres are matrix systems in which the drug is physically and uniformly dispersed.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302817/
Dec 18, 2018 · Such a NP system for drug delivery is multifunctional, providing a way to formulate anticancer drugs with no use of harmful adjuvants, reducing the side effects of the formulated anticancer drug, promoting synergistic therapeutic effects with cancer immune checkpoints, and achieving targeted delivery of the therapy.Author: Shijie Xu, Fangbo Cui, Dafu Huang, Dinghu Zhang, Anqing Zhu, Xia Sun, Yiming Cao, Sheng Ding, Yao Wa...
https://www.sciencedirect.com/science/article/pii/S1773224719316727
Specific and efficient drug delivery is a fundamental challenge in clinical therapies and is shifting attentions to carriers such as albumin in recent years [8,9]. The aim of this study is to review features of various albumins and their applications as nanocarriers focusing on antibody and nanobody delivery.Author: Elmira Karami, Mahdi Behdani, Fatemeh Kazemi-Lomedasht
https://www.sciencedirect.com/science/article/pii/S0939641108003378
Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB) ... The number of mAb molecules bound on the surface of a single nanoparticle was calculated using the equation published by Cirstoiu-Hapca et al. .Author: Karsten Ulbrich, Telli Hekmatara, Elisabeth Herbert, Jörg Kreuter
https://www.hindawi.com/journals/jir/2018/3673295/
2.1. Combination PDT with Checkpoint Blockade Antibody. Nanoparticle-based photodynamic therapy (PDT) was commonly combined with checkpoint blockade immunotherapy because PDT could induce immunogenic cell death (ICD) . Yang et al. constructed a multistage responsive drug delivery system based on hollow silica nanoparticles . The nanoparticles ...Author: Huan Zhao, Yuanqi Li, Dan Wei, Hongrong Luo
https://www.europeanpharmaceuticalreview.com/news/113823/nanoparticle-drug-delivery-could-be-the-future-of-targeted-cancer-therapies/
Nanoparticle gene therapy drug delivery for paediatric brain cancer tested in mice… Imaging reveals nanoparticle distribution and excretion …a nanoparticle of exactly three nanometres and certain sized antibody fragments had a positive influence on the distribution and retention of …
https://www.future-science.com/doi/full/10.4155/fdd-2019-0005
Jul 01, 2019 · The goal of this study was to investigate these antibodies as targeting ligands for nanoparticle-mediated drug delivery. Methods: Paclitaxel-loaded poly(D,L-lactide-co-glycolide) nanoparticles were functionalized with antibodies using thiol–maleimide chemistry.Author: Vidhi Khanna, Stephen Kalscheuer, Ameya Kirtane, Wenqiu Zhang, Jayanth Panyam
https://pubs.acs.org/doi/10.1021/mp900316a
Current chemotherapy regimens against pancreatic cancer are met with little success as poor tumor vascularization significantly limits the delivery of oncological drugs. High-dose targeted drug delivery, through which a drug delivery vehicle releases a large payload upon tumor localization, is thus a promising alternative strategy against this lethal disease. Herein, we synthesize anti ...Author: Che Ming Jack Hu, Sharmeela Kaushal, Hop S. Tran Cao, Santosh Aryal, Marta Sartor, Sadik Esener, Mic...
https://www.nature.com/articles/nbt.4181
In vivo targeting of adoptively transferred T cells with antibody- and ... L., Zheng, Y., Melo, M. et al. Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery ...Author: Li Tang, Yiran Zheng, Mariane Bandeira de Melo, Llian Mabardi, Ana P. Castaño, Yu-Qing Xie, Na Li, S...
https://www.researchgate.net/publication/272148044_Computational_Modeling_of_Nanoparticle_Targeted_Drug_Delivery
Computational Modeling of Nanoparticle Targeted Drug Delivery Liu et al. and c s surface concentration of adsorbed species (mol/m 2 5 . Note that c s is different from c which is reflected in their
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