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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Although solid NPs may be used for drug targeting, when reaching the intended diseased site in the body the drug carried needs to be released. So, for drug delivery biodegradable nanoparticle formulations are needed as it is the intention to transport and release the drug in order to be effective.Author: Wim H De Jong, Paul Ja Borm
https://www.sciencedirect.com/science/article/abs/pii/S1734114012709015
Cell-specific targeting can be accomplished by attaching drugs to specially designed carriers. Various nanostructures, including liposomes, polymers, dendrimers, silicon or carbon materials, and magnetic nanoparticles, have been tested as carriers in drug delivery systems.Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://www.pnas.org/content/108/6/2426
Feb 08, 2011 · Multistage nanoparticle systems provide additional tunability in the spatial control of delivery to solid tumors. Because of the multiple physiological barriers that a therapeutic agent must encounter, a multistage nanoparticle system can enhance penetration by changing its size, charge, shape, flexibility, and/or surface coating to suit the ...Author: Cliff Wong, Triantafyllos Stylianopoulos, Jian Cui, John Daniel Martin, Vikash P. Chauhan, Wen Jiang...
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The use of ideal nano-drug delivery system is decided primarily based on the biophysical and biochemical properties of the targeted drugs being selected for the treatment . However, problems such as toxicity exhibited by nanoparticles cannot be ignored when considering the use of nanomedicine.Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559243/
NANOPARTICLE DELIVERY SYSTEMS IN CANCER VACCINES. ... Therapeutic strategies that involve the manipulation of the host’s immune system are gaining momentum in cancer research. Antigen-loaded nanocarriers are capable of being actively taken up by antigen presenting cells (APCs) and have shown promising potential in cancer immunotherapy by ...Author: Yogita Krishnamachari, Sean M. Geary, Caitlin D. Lemke, Aliasger K. Salem
https://f1000research.com/articles/6-681
May 16, 2017 · Introduction. With their unique physical and chemical properties as well as their nanoscale effects, nanoparticle-based drug delivery systems (NDDSs) are currently under extensive development for applications in the treatment of diseases such as cardiovascular diseases, infectious diseases, diabetes, and cancer 1–3.It has been reported that most cancers, as malignant diseases, …Author: Yi-Feng Wang, Yi-Feng Wang, Lu Liu, Lu Liu, Xue Xue, Xing-Jie Liang, Xing-Jie Liang
https://patents.google.com/patent/US10322089B2/en
nanoparticle nanoparticles delivery Prior art date 2012-03-14 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Active, expires 2035-07-19 Application number US13/799,883 Other versions US20130243848A1 (en ...Author: Tatsiana Lobovkina, Gunilla B. Jacobson, Richard N. Zare, Evgenios Neofytou, Ramin E. Beygui, Marie ...
https://pubs.acs.org/doi/full/10.1021/ar500217w
Conspectus“Smart” stimuli-responsive nanomaterials are becoming popular as targeted delivery systems because they allow the use of internal or external stimuli to achieve spatial or temporal control over the delivery process. Among the stimuli that have been used, light is of special interest because it is not only noninvasive but also controllable both spatially and temporally, thus ...Author: Akshaya Bansal, Yong Zhang
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