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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Hydrogel-nanoparticles are based on proprietary technology that uses hydrophobic polysaccharides for encapsulation and delivery of drug, therapeutic protein, or vaccine antigen. A novel system using cholesterol pullulan shows great promise.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The aims for nanoparticle entrapment of drugs are either enhanced delivery to, or uptake by, target cells and/or a reduction in the toxicity of the free drug to non-target organs. Both situations will result in an increase of therapeutic index, the margin between the doses resulting in a therapeutic efficacy (eg,...Author: Wim H De Jong, Paul Ja Borm
https://f1000research.com/articles/6-681
May 16, 2017 · Nanoparticle-based drug delivery systems as a drug-like modulator for therapy. NDDSs have always been used as a vehicle to deliver therapeutic drugs or imaging agents. Their physicochemical characteristics are carefully optimized to meet the demand of delivery and targeting.Author: Yi-Feng Wang, Yi-Feng Wang, Lu Liu, Lu Liu, Xue Xue, Xing-Jie Liang, Xing-Jie Liang
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES Considerable research and development is devoted to improving drug delivery through the use of nanoparticles.
https://www.sciencedirect.com/science/article/pii/B9780128136898000021
Nanoparticle drug delivery systems (NPDDS) achieve superior entry for the particles inside the body, as their size permits conveyance by means of intravenous infusion or different courses. Another important use of the NPDDS is in the production of the antibodies based specific proteins against the …Author: Deepti Sharma, Navneet Sharma, Mallika Pathak, Paban K. Agrawala, Mitra Basu, Himanshu Ojha
https://link.springer.com/article/10.1007/s40005-016-0252-1
May 19, 2016 · Nanoparticle-mediated chemotherapeutic delivery is a promising approach for the effective treatment of various cancers because it may simultaneously enhance therapeutic effects and reduce side effects. The loading of multiple chemotherapeutic agents to these systems could additionally improve the antineoplastic efficacy.Author: Ju Yeon Choi, Raj Kumar Thapa, Chul Soon Yong, Jong Oh Kim
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Nanomedicine is the branch of medicine that utilizes the science of nanotechnology in the preclusion and cure of various diseases using the nanoscale materials, such as biocompatible nanoparticles [ 35] and nanorobots [ 36 ], for various applications including, diagnosis [ 37 ], delivery [ 38 ], sensory [ 39 ],...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.sciencedirect.com/science/article/abs/pii/S1734114012709015
Cell-specific targeting can be accomplished by attaching drugs to specially designed carriers. Various nanostructures, including liposomes, polymers, dendrimers, silicon or carbon materials, and magnetic nanoparticles, have been tested as carriers in drug delivery systems.Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://www.hindawi.com/journals/jnm/2016/1087250/
Nanoparticles have shown promise as both drug delivery vehicles and direct antitumor systems, but they must be properly designed in order to maximize efficacy. Computational modeling is often used both to design new nanoparticles and to better understand existing ones. Modeled processes include the release of drugs at the tumor site and the physical interaction between the nanoparticle and ...Author: Xiaojiao Yu, Ian Trase, Muqing Ren, Kayla Duval, Xing Guo, Zi Chen
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