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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The non restricted (cyto)toxicity of chemotherapeutics thus limits the full use of their therapeutic potential. Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as …Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
It produces significant tumor growth inhibition and regression in mouse xenografts and lymphoma in dogs, despite administration of minute amounts of drug and antibody. Indeed, reduced dosage is a critical factor for limiting systemic toxicity. Clinical trials are planned for testing this method of drug delivery.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/965.pdf
have gained more attention as drug delivery carriers because of their better stability,low toxicity,simple and mild preparation method and providing versatile routes of administration. Alginate nanoparticles is a anionic polysaccharide taht it has been widely used in drug delivery. Its
https://www.sciencedirect.com/science/article/pii/S1319016411000302
1. Nanoparticles. Conventional preparations like solution, suspension or emulsion suffer from certain limitations like high dose and low availability, first pass effect, intolerance, instability, and they exhibit fluctuations in plasma drug levels and do not provide sustained effect, therefore there is a need for some novel carriers which could meet ideal requirement of drug delivery system.Author: Sagar R. Mudshinge, Amol B. Deore, Sachin Patil, Chetan M. Bhalgat
https://www.nanowerk.com/how_nanoparticles_are_made.php
Nanoparticles are materials that are confined to the nanoscale in all three dimensions. Engineered nanoparticles play an important role in nanotechnology. The specific properties of nanoparticles is defined by particle size, chemical composition, crystallinity and shape. During production these can be controlled by temperature, pH-value, concentration, chemical composition, surface ...
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