Mucosal Delivery

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Oral mucosal drug delivery: clinical pharmacokinetics and ...

    https://www.ncbi.nlm.nih.gov/pubmed/12126458
    For analgesics that are used to treat mild to moderate pain, rapid onset has relatively little benefit and oral mucosal delivery is a poor option. Oral mucosal delivery of sedatives such as midazolam, triazolam and etomidate has shown favourable results with clinical advantages over other routes of administration.Author: Hao Zhang, Jie Zhang, James B. Streisand

Alternative Methods of Vaccine Delivery: An Overview of ...

    https://www.hindawi.com/journals/jir/2019/8303648/
    The Mucosal Delivery and the Immune Response. The efficacy of the mucosal administration route is largely based on the fact that mucous membranes constitute the largest immunologic organ in the body. Moreover, this interface is endowed with well-organized lymphatic structures, ...Author: E. Criscuolo, V. Caputo, V. Caputo, R. A. Diotti, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum, N. ...

A DETAILED REVIEW ON ORAL MUCOSAL DRUG DELIVERY …

    http://ijpsr.com/bft-article/a-detailed-review-on-oral-mucosal-drug-delivery-system/?view=fulltext
    ABSTRACT:Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora.Oral mucosal drug delivery system provides local and systemic action. In this review, attention is focused to give regarding physiology of oral mucosal ...

Mucosal delivery of fish vaccines: Local and systemic ...

    https://www.sciencedirect.com/science/article/pii/S105046482030005X
    1. Introduction. Mucosal vaccines employed for humans and animals include oral, nasal, sublingual and genital tract vaccines, which have many advantages when compared to systemic vaccines in terms of means of delivery and stimulation of the immune system [].Simple means of delivery which are needle-free administrations results in low stress for vaccine recipients and administrators.Author: Tomonori Somamoto, Teruyuki Nakanishi

Mucus-penetrating nanoparticles for drug and gene delivery ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667119/
    Feb 27, 2009 · Mucus is a viscoelastic and adhesive gel that protects the lung airways, gastrointestinal (GI) tract, vagina, eye and other mucosal surfaces. Most foreign particulates, including conventional particle-based drug delivery systems, are efficiently trapped in human mucus layers by steric obstruction and/or adhesion.Author: Samuel K. Lai, Ying Ying Wang, Justin S Hanes

Mucosal Drug Delivery: Membranes, Methodologies, and ...

    https://www.researchgate.net/publication/8460157_Mucosal_Drug_Delivery_Membranes_Methodologies_and_Applications
    Like other mucosal delivery routes, drug transport across the vaginal membrane may occur by a number of different mechanisms namely (a) diffusion through cell according to concentration gradient ...

MAD Nasal™ Intranasal Mucosal Atomization Device US ...

    https://www.teleflex.com/usa/en/product-areas/anesthesia/atomization/mad-nasal-device/index.html
    The MAD Nasal ™ Intranasal Mucosal Atomization Device from Teleflex is the safe and painless way to deliver medications*. Atomizes in any position; The soft, conical plug on the tip forms a seal with the nostril, preventing expulsion of fluid ... Suresh M. Management of Predicted Difficult Airway in A Parturient Undergoing Cesarean Delivery ...

Mucosal Drug Delivery Applied Physical Sciences

    https://aps.unc.edu/home-page-news-item/one-step-closer-to-overcoming-the-mucus-barrier-in-mucosal-drug-delivery/
    May 24, 2018 · In mucosal drug delivery, two design goals are desirable: 1) insure drug passage through the mucosal barrier to the epithelium prior to drug removal from the respective organ via mucus clearance; and 2) design carrier particles to achieve a prescribed arrival time and drug uptake schedule at the epithelium. Both goals are achievable if one can ...

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