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https://www.sciencedirect.com/science/article/pii/S0378517302006324
Therefore, it would be possible to incorporate even lower concentrations of estradiol in the microemulsions and still provide adequate total estradiol flux across the skin of reasonable surface area. 4. Conclusions. The utility of microemulsions as vehicles for topical delivery of estradiol was studied.Author: S Peltola, P Saarinen-Savolainen, J Kiesvaara, T.M Suhonen, A Urtti
https://www.researchgate.net/publication/10868498_Microemulsions_for_topical_delivery_of_estradiol
The purpose of this study was to investigate microemulsions as delivery systems for estradiol. Various o/w microemulsions were used to deliver estradiol across human abdominal skin in vitro.
https://www.researchgate.net/publication/5554643_Microemulsions_Applications_in_Transdermal_and_Dermal_Delivery
Microemulsions have gained much interest as second-generation colloidal carrier systems for the dermal/transdermal delivery of the various hydrophilic and lipophilic drugs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167257/
Jul 02, 2011 · Microemulsions have several advantages such as enhanced drug solubility, good thermodynamic stability, and higher transdermal permeability over conventional formulations (11,12). Many studies reported the use of microemulsions as topical drug delivery vehicles showed their ability to improve transdermal and dermal delivery properties (12–15).Author: Fahima M. Hashem, Dalia S. Shaker, Mohamed Khalid Ghorab, Mohamed Nasr, Aliaa Ismail
https://www.deepdyve.com/lp/elsevier/microemulsions-for-topical-delivery-of-estradiol-WTCUj0cT05
Mar 26, 2003 · Read "Microemulsions for topical delivery of estradiol, International Journal of Pharmaceutics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
http://europepmc.org/abstract/MED/12623186
Apr 01, 2003 · The purpose of this study was to investigate microemulsions as delivery systems for estradiol. Various o/w microemulsions were used to deliver estradiol across human abdominal skin in vitro. Trasdermal flux of estradiol was determined using Franz-type diffusion cells and the samples were analyzed by high-performance liquid chromatography (HPLC).Author: S Peltola, P Saarinen-Savolainen, J Kiesvaara, T.M Suhonen, A Urtti
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699131/
The aim of this study was to evaluate the potential of microemulsions as a drug vehicle for transdermal delivery of citalopram. A computerized statistical technique of response surface methodology with mixture design was used to investigate and optimize ...Author: Chi-Te Huang, Ming-Jun Tsai, Yu-Hsuan Lin, Yaw-Sya Fu, Yaw-Bin Huang, Yi-Hung Tsai, Pao-Chu Wu
https://www.sciencedirect.com/science/article/pii/S0378517306001372
The purpose of this study was to construct microemulsion-base hydrogel formulation for topical delivery of ibuprofen. Ethyl oleate (EO) was screened as the oil phase of microemulsions, due to a good solubilizing capacity of the microemulison systems and excellent skin permeation rate of ibuprofen.Author: Huabing Chen, Xueling Chang, Danrong Du, Jin Li, Huibi Xu, Xiangliang Yang
https://www.hindawi.com/journals/isrn/2011/780150/
Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. The pseudoternary phase diagrams were constructed to determine the composition of microemulsions. The insulin permeation flux of microemulsions containing oleic acid as oil phase through excised ...Author: Jadupati Malakar, Suma Oomen Sen, Amit Kumar Nayak, Kalyan Kumar Sen
http://michniaklab.org/our-science/topical-transdermal-buccal-drug-delivery/microemulsions-for-transdermal-and-topical-drug-delivery/
Microemulsion internal structural domains are in the micro/nano-scale, typically in the range of 10 – 200 nm. For transdermal and topical drug delivery applications, microemulsions have demonstrated effectiveness in enhancing drug skin permeation and/or skin drug deposition.
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