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https://www.sciencemag.org/news/2010/03/researchers-turn-mosquitoes-flying-vaccinators
Nov 01, 2019 · A group of Japanese researchers has developed a mosquito that spreads vaccine instead of disease. Even the researchers admit, however, that regulatory and ethical problems will prevent the critters...
https://longitudes.ups.com/tedups-what-if-mosquitoes-could-deliver-vaccines/
Regarding vaccine delivery specifically, I wanted to bring to light the struggles of delivering medical attention to underdeveloped communities around the world. Finding solutions for people living in these areas is a huge opportunity for businesses, and if I inspired just one other person think about how to reach these communities, then it was worth it.
https://www.sciencedaily.com/releases/2013/09/130911093049.htm
Sep 11, 2013 · July 13, 2018 — Researchers have created a vaccine that protects against malaria infection in mouse models, paving the way for the development of a human vaccine …
https://www.medscape.com/viewarticle/581891
Oct 18, 2019 · Most commercial vaccines available today are delivered by injection, with problems of safety, patient acceptability and morbidity. In recent years, there have been advances in methods of needle-free vaccine delivery, among which, oral delivery is of particular interest. [1,2,3] Oral delivery offers a number...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607064/
Mar 25, 2013 · Nanoparticles as vaccine delivery vehicles. Traditional vaccines include live attenuated microbes, killed microbes, or components of microbes. Although many of these vaccines have been central to the control of infectious disease, some do not afford good protection against disease.Author: Anthony E. Gregory, Richard Titball, Diane Williamson
https://www.nih.gov/news-events/news-releases/nih-begins-study-vaccine-protect-against-mosquito-borne-diseases
“A single vaccine capable of protecting against the scourge of mosquito-borne diseases is a novel concept that, if proven successful, would be a monumental public health advance.” Led by Matthew J. Memoli, M.D., director of the Clinical Studies Unit in NIAID’s Laboratory of Infectious Diseases, the clinical trial is expected to enroll up to 60 healthy adults ages 18 to 50 years.
https://www.cdc.gov/dengue/prevention/dengue-vaccine.html
Sep 23, 2019 · Dengue Vaccine Globally. A vaccine to prevent dengue (Dengvaxia®) is licensed and available in some countries for people ages 9-45 years old. The World Health Organization recommends that the vaccine only be given to persons with confirmed prior dengue virus infection.
https://academic.oup.com/jid/article/218/1/7/4956143
Mar 29, 2018 · Mosquito saliva-based vaccine: proposed mechanism of action. (A) A virus-infected mosquito seeks a blood meal while injecting salivary proteins and viral particles from its salivary glands. The bite trauma coupled with the salivary effects cause vascular leakage, edema, mast cell degranulation, and release of host Th2-predominant cytokines.Author: Jessica E Manning, David M Morens, Shaden Kamhawi, Jesus G Valenzuela, Matthew Memoli
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077160/
The company Sanaria was founded to translate the mosquito-based immunization approach into injectable whole PfSPZ malaria vaccines, and to use the vaccine(s) to eliminate malaria from geographically defined areas through mass immunization and to prevent malaria in non-immune visitors to malarious areas.Author: Stephen L. Hoffman, Johan Vekemans, Thomas L. Richie, Patrick E. Duffy
https://www.seattletimes.com/seattle-news/science/mosquitoes-are-the-new-syringe-seattle-lab-nibbles-at-malaria-vaccine/
Seattle lab nibbles at malaria vaccine. Originally published January 4, 2017 at 11:10 am Updated January 4, 2017 at 8:23 pm. A Seattle lab’s unconventional approach to a malaria vaccine, once dismissed as crazy, worked well in early tests but faces a long road to reality.
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