Microtrol Extended Release Delivery System

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Microtrol® Technology Trokendi XR® (topiramate) HCP

    https://www.trokendixrhcp.com/clinical-data/delivery-technology/
    Extended-release beads have a special coating that allows for drug delivery throughout the dosing interval Trokendi XR® (topiramate) capsules contain thousands of specially coated beads that use Microtrol technology to help maintain consistent drug levels throughout the day for predictable topiramate delivery 1

Microtrol - Wikipedia

    https://en.wikipedia.org/wiki/Microtrol
    Microtrol is an extended-release drug delivery system. It is used in certain medications like Adderall and incorporates two types of beads. The first dissolves immediately, releasing half of the medication, while the second type dissolves much more slowly releasing the remaining medication four hours later.

Microtrol® Technology Delivery Trokendi XR® (topiramate)

    http://www.trokendixrhcp.utdev.com/clinical-data/microtrol-delivery/
    Extended-release beads have a special coating that allows for drug delivery throughout the dosing interval Trokendi XR capsules contain thousands of specially coated beads that use Microtrol technology to help maintain consistent drug levels throughout the day for predictable topiramate delivery 1

Kinetics of Microtrol, extended-release drug delivery ...

    https://www.researchgate.net/post/Kinetics_of_Microtrol_extended-release_drug_delivery_system_of_Adderall_XR2
    Paracetamol suppositories made with PEG 4000 and PEG 6000 as suppository bases undergo dissolution test. After 45 minutes, both batches have mean % of drug release that is higher than 100%.

How long does it take an extended release pill to be ...

    https://ask.metafilter.com/62390/How-long-does-it-take-an-extended-release-pill-to-be-completely-disolved-into-your-bloodstream
    May 11, 2007 · Adderall XR utilizes the Microtrol® delivery system to achieve the extended-release mechanism. This delivery system incorporates two beads: the first type of bead dissolves immediately and the second type releases four hours later. Maximum plasma concentration is achieved in seven hours. posted by sanko at 8:04 AM on May 11, 2007

Extended release peptide delivery systems through the use ...

    https://www.tandfonline.com/doi/abs/10.1163/156856200743977
    Apr 19, 2000 · Additionally, a single polymer system composed of a high molecular weight ester terminated 75:25 PLGA was employed to produce release over the desired 90-day release period. This study demonstrates that microsphere combinations can potentially provide effective therapies over extended intervals when combined at the proper ratio.Author: K. W. Burton, M. Shameem, B. C. Thanoo, P. P. Deluca

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