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https://www.sciencedirect.com/science/article/pii/S0264410X18307539
Microparticles formed for oral vaccine delivery are internalized in the intestinal tissues through the M-cell rich lymphoid aggregates . This is because of the resemblance of microparticles in shape and size to bacteria which also follow this non-phagocytic route of internalization.Author: Ebele Onuigbo, Joy Iseghohimhen, Kennedy Chah, Moses Gyang, Anthony Attama
https://www.researchgate.net/publication/7471402_Microparticles_for_oral_delivery_of_vaccines_Expert_Opin_Drug_Deliv_2791-806
Studies in laboratory animals have clearly demonstrated that microparticles can significantly improve the immunogenicity of orally administered antigens. However, the oral delivery of vaccines...
https://www.ncbi.nlm.nih.gov/pubmed/30017142
Aug 09, 2018 · Chitosan/alginate microparticles for the oral delivery of fowl typhoid vaccine: Innate and acquired immunity. Onuigbo E(1), Iseghohimhen J(2), Chah K(3), Gyang M(4), Attama A(5). Author information: (1)Department of Pharmaceutical Microbiology and Biotechnology, University of …Author: Ebele Onuigbo, Joy Iseghohimhen, Kennedy Chah, Moses Gyang, Anthony Attama
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.0105-2896.2004.00153.x
One effective means of facilitating delivery of DNA vaccines to APCs is through the use of microparticles. In this article, we review the background and rationale for microparticles as a vaccine delivery system, data demonstrating their utility and mode of action for DNA delivery, and the prospects for their development.Author: Derek T. O'Hagan, Manmohan Singh, Jeffrey B. Ulmer
https://www.sciencedirect.com/science/article/pii/S0169409X98000453
Microparticles and polymers for the mucosal delivery of vaccines 1. Introduction. The oral route of delivery is the most attractive and acceptable,... 2. The intestinal uptake of microparticles. 3. Microparticles for oral delivery of drugs. 4. Microparticles for oral delivery of vaccines. 5. ...Author: Derek T. O'Hagan
https://www.ncbi.nlm.nih.gov/pubmed/22283700
Spray-dried microparticles: a potential vehicle for oral delivery of vaccines. Chablani L(1), Tawde SA, D'Souza MJ. Author information: (1)Vaccine Nanotechnology Laboratory, Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Mercer University, Atlanta, GA 30341, USA.Author: Lipika Chablani, Suprita A. Tawde, Martin J. D'souza
https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2017.1282589
conventional DNA, peptide and tumor cell-based vaccines for oral delivery. Thus, new strategies that can overcome the bar-riers of oral delivery are urgently needed for developing high efficacious and efficient tumor vaccines. Despite the delivery barriers, other issues are also challeng-ing for eliciting effective antitumor T cell immunity ...
https://www.researchgate.net/publication/258508916_Development_of_Polymeric_Microparticles_for_the_Delivery_of_Oral_Vaccine
These microparticles possibly act as the appropriate protein delivery system targeting to peyer's patches of small intestine for oral vaccine.
https://pubs.rsc.org/en/content/articlelanding/2016/tb/c5tb01623a
Microparticle-based strategies are attractive for oral vaccination due to their ability to efficiently penetrate the mucus barrier and have the added advantage of protecting the antigen in …Author: Joshua D. Snook, Charles B. Chesson, Alex G. Peniche, Sara M. Dann, Adriana Paulucci, Iryna V Pinchu...
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