Microneedles For Ocular Drug Delivery

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Minimally invasive microneedles for ocular drug delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/27485251
    Minimally invasive microneedles for ocular drug delivery. ... Expert opinion: MNs can aid in localization of drug delivery systems within the selected ocular tissue. And, hold the potential to revolutionize the way drug formulations are administered to the eye. However, the current limitations and challenges of MNs application warrant further ...Author: Raghu Raj Thakur Singh, Ismaiel Tekko, Kathryn McAvoy, Hannah McMillan, David Jones, Ryan F. Donnell...

Fenestrated microneedles for ocular drug delivery ...

    https://www.sciencedirect.com/science/article/pii/S0925400515303786
    The development of a safe, simple, and efficacious means for ocular drug delivery remains a critical unmet need. Solid microneedles (MNs) show significant promise in this regard.Author: Omid Khandan, Malik Y. Kahook, Masaru P. Rao

Rapidly dissolving polymeric microneedles for minimally ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097091/
    Oct 05, 2016 · In this study, dissolving microneedles (MNs) were used to enhance ocular drug delivery of macromolecules. MNs were fabricated using polyvinylpyrrolidone (PVP) polymer of various molecular weights (MWs) containing three model molecules of increasing MW, namely fluorescein sodium and fluorescein isothiocyanate–dextrans (with MW of 70 k and 150 k Da).Author: Raghu Raj Singh Thakur, Ismaiel A. Tekko, Ismaiel A. Tekko, Farhan Al-Shammari, Ahlam A. Ali, Helen ...

Current Perspective on microneedles for ocular drug delivery

    https://www.researchgate.net/publication/319287807_Current_Perspective_on_microneedles_for_ocular_drug_delivery
    There are few reports that large molecules, proteins, vaccines could be delivered into eye using microneedles. Drug delivery to the posterior segment of the eye is a significantly challenging task ...

OCULAR DRUG DELIVERY USING MICRONEEDLES

    http://drugdelivery.chbe.gatech.edu/Papers/Thesis/Jiang_Ninghao_thesis.pdf
    OCULAR DRUG DELIVERY USING MICRONEEDLES Approved by: Dr. Mark R. Prausnitz, Chairman Dr. Athanassios Sambanis School of Chemical & Biomolecular Engineering School of Chemical & Biomolecular Engineering Georgia Institute of Technology Georgia Institute of Technology Dr. Mark G. Allen Dr. Henry F. Edelhauser

Microneedles for Ocular Drug Delivery and Targeting ...

    https://onlinelibrary.wiley.com/doi/10.1002/9781119305101.ch10
    Jun 22, 2018 · It also provides an overview of the limitations and difficulties of application of microneedles (MNs) in ocular drug delivery and its prospects. MNs were developed as a painless, minimally invasive and effective technology for transdermal drug delivery.Author: Ismaiel A. Tekko, Ismaiel A. Tekko, Thakur Raghu Raj Singh

Eye Patch Uses Microneedles for Ocular Drug Delivery ...

    https://insights.globalspec.com/article/10569/eye-patch-uses-microneedles-for-ocular-drug-delivery
    Nov 26, 2018 · Eye Patch Uses Microneedles for Ocular Drug Delivery S. Himmelstein | November 26, 2018 The eye-contact patch for ocular drug delivery is equipped with an array of self-implantable micro-drug-reservoirs. Source: NTU Singapore. Current methods for treating eye diseases, such as glaucoma and macular degeneration, rely on eye drops and ...

Self-implantable double-layered micro-drug-reservoirs for ...

    https://www.nature.com/articles/s41467-018-06981-w
    Nov 06, 2018 · These microneedles can penetrate the ocular surface tissue, and serve as implanted micro-reservoirs for controlled drug delivery. The biphasic drug …Author: Aung Than, Chenghao Liu, Hao Chang, Phan Khanh Duong, Chui Ming Gemmy Cheung, Chenjie Xu, Xiaomeng W...

Microneedles for enhanced transdermal and intraocular drug ...

    https://www.sciencedirect.com/science/article/pii/S1471489217300826
    If one transdermal drug delivery product based on MN receives regulatory approval and reaches the market, it is likely that many others will quickly follow. Application of microneedles for ocular drug delivery. Ocular delivery of medications has proved challenging to formulation scientists and retinal experts.Author: Kurtis Moffatt, Yujing Wang, Thakur Raghu Raj Singh, Ryan F Donnelly

Minimally invasive microneedles for ocular drug delivery

    https://pure.qub.ac.uk/files/72078099/s1_ln24102598474996832_1939656818Hwf1576690458IdV175442731424102598PDF_HI0001.pdf
    application for ocular drug delivery, which is aimed to benefit researchers in this field. 2. Challenges and Obstacles of Ocular Drug Delivery Although eye offers a convenient site for drug administration for various conditions, there are many challenges. Drug delivery research has significantly increased for

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