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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794664/
Oct 14, 2019 · Keywords: microneedle, transdermal drug delivery, drug delivery methods, materials, structures, fabricating methods Introduction Skin is an important organ evolved to protect the body against unwanted influences, such as excessive water loss, …
https://onlinelibrary.wiley.com/doi/full/10.1111/j.2042-7158.2011.01369.x
Transdermal drug delivery system is an emerging area for systemic as well as local delivery of macromolecules. The biggest drawback of TDDS is poor permeability through stratum corneum and it can be overcome by using microneedles.Author: Shital H. Bariya, Mukesh C. Gohel, Tejal A. Mehta, Om Prakash Sharma
https://www.researchgate.net/publication/51860989_Microneedles_An_Emerging_Transdermal_Drug_Delivery_System
drug delivery system can be explored as a potential tool for the delivery of a variety of macromolecules that are not effectively delivered by c onventional transdermal techniques.
https://www.sciencedirect.com/science/article/pii/S0753332218348091
Microneedle device consists of needles of micron size, which are arranged on a small patch. Considering the problems of the hypodermic needle and the transdermal patch, microneedle drug delivery system was developed and is thought to be the hybrid of both.Author: Tejashree Waghule, Gautam Singhvi, Sunil Kumar Dubey, Murali Monohar Pandey, Gaurav Gupta, Mahaveer ...
https://www.sciencedirect.com/science/article/pii/S0169409X03002394
Since the first studies of transdermal drug delivery in 1998 , there has been rapidly increasing interest in the field, with most activity in the microfabrication community to develop novel needle fabrication technologies and the drug delivery industry to develop microneedles for pharmaceutical applications. 2.Author: Mark R Prausnitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300505/
A patchless dissolving microneedle delivery system enabling rapid and efficient transdermal drug delivery Shayan F. Lahiji , 1 Manita Dangol , 1 and Hyungil Jung a, 1 1 Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-749, KoreaAuthor: Shayan F. Lahiji, Manita Dangol, Hyungil Jung
https://www.tandfonline.com/doi/abs/10.1080/13543776.2020.1742324
Due to this, transdermal drug delivery systems (TDDS) can minimize several problems associated with conventional drug delivery. The development of microneedle (MNs) arrays is an approach which allows drug delivery through the skin by improving safety, efficacy and bioavailability.
https://www.researchgate.net/publication/261759007_TRANSDERMAL_DRUG_DELIVERY_SYSTEM_A_REVIEW
Transdermal drug delivery system (TDDS) is topically administered dosage form in the form of patches which deliver drugs for systemic effects at a predetermined and controlled rate.
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/microneedle/
3M Microneedle Drug Delivery Systems, which include Hollow Microneedle and Solid Microneedle technology, offer patient-friendly delivery solutions for vaccines or difficult-to-deliver biologics for particularly needle-phobic patients. By potentially reducing anxiety, microneedle delivery may improve patient compliance in some patient groups.
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