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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764637/
Microgels composed of mucoadhesive polymers may be used to design new types of carriers for oral and non-oral drug delivery [4,5,6]. Understanding of the surface interactions between hydrophilic polymer surfaces and mucins could lead to improved adhesion.Author: Serguei V. Vinogradov
https://www.sciencedirect.com/topics/engineering/microgels
These abilities make microgels as an improved class of hydrogel matrices with some important properties such as controlling drug-binding and drug-releasing kinetics, long-standing stability and better shelf life, biodegradation, biodistribution, bioaccumulation, biotargeting, and functionality in perspective of the uses in drug delivery (Vinogradov, 2006; Smeets and Hoare, 2013).
https://www.onlinelibrary.wiley.com/doi/full/10.1002/pola.26707
Microgels have been used as drug delivery vehicles for low‐molecular‐weight compounds such as dexamethasone and bupivacaine 89 as well as biomacromolecules such as fluorescein‐labeled dextran, 90 insulin, 8, 91 and bovine serum albumin (BSA). 92, 93 The binding of these drugs is greatly impacted by the local crosslink density and the functional group distribution within the microgel. 94, 95 …Author: Niels M. B. Smeets, Todd Hoare
https://www.intechopen.com/books/pharmaceutical-formulation-design-recent-practices/ph-responsive-microgels-promising-carriers-for-controlled-drug-delivery
Microgels are microscopic hydrogels and have attracted much attention as vehicle for drug delivery. Stimuli-responsive MGs are smart drug delivery carriers and have the capability to incorporate and release their host molecules in response to stimuli (pH, ionic strength, and temperature), for targeted drug delivery.Author: Zermina Rashid
https://www.sciencedirect.com/science/article/pii/S007967000900080X
Biopolymer-based microgels/nanogels (biomicrogels/bionanogels) have recently attracted a great deal of interest in tissue engineering and drug delivery applications , , . The development of various biopolymer-based hydrogels has been also explored , , , , , , , , , , . They have all the properties of synthetic counterparts as well as being intrinsically biodegradable, abundant in nature, renewable, nontoxic, …Author: Jung Kwon Oh, Do Ik Lee, Jong Myung Park
https://www.sciencedirect.com/science/article/pii/S1742706119301151
Microgel systems have emerged as drug and growth factor delivery systems that have tailorable release kinetics , including those that possess the potential for specified release based on surrounding pH , and microgels can even be combined for dual drug delivery . In general, hydrogels are good materials for bioactive factor encapsulation due to their hydrophilic nature and often gentle fabrication and …Author: Jake P. Newsom, Karin A. Payne, Melissa D. Krebs
https://www.ncbi.nlm.nih.gov/pubmed/17168773
Colloidal microgels have recently received attention as environmentally responsive systems and now are increasingly used in applications as carriers for therapeutic drugs and diagnostic agents. Synthetic microgels consist of a crosslinked polymer network that provides a depot for loaded drugs, protection against environmental hazards and template for post-synthetic modification or vectorization of the drug carriers.Author: Serguei V. Vinogradov
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