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https://pubs.rsc.org/en/content/articlelanding/2011/lc/c1lc20766k#!
Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and optimization of multiple processes and techniques used in gene transfection and the production of gene …
https://www.researchgate.net/publication/51745758_Microfluidic_approaches_for_gene_delivery_and_gene_therapy
Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and...
https://ufluidix.com/microfluidics-applications/gene-delivery/
Microfluidic technology for efficient and high yield gene delivery Transfection is the process of delivering a genetic cargo into the cells. The main challenge for both therapeutic and diagnostic use of genetic methods such as CRISPR-Cas is the low transfection rate.
https://www.mdpi.com/2073-4425/9/2/103/htm
Microfluidic devices present unique advantages for the development of efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Compared to bulk methods, by efficiently controlling the geometries of the fabricated chip and the flow rates of multiphase fluids, microfluidic …Author: Samar Damiati, Uday B. Kompella, Safa A. Damiati, Rimantas Kodzius
http://www.eurekaselect.com/126121
This article provides an overview of recent advances in microfluidic gene delivery, and speculates the prospects for further research. The objectives of this article are to illustrate the potential roles played by microfluidics in gene delivery research, and to shed new light on strategies to enhance the efficiency of gene therapy.Author: Wing-Fu Lai
https://www.sciencedirect.com/science/article/pii/S0927776513002427
Microfluidic devices for continuous production of pDNA/cationic liposome complexes for gene delivery and vaccine therapy 1. Introduction. Microfluidics is a multidisciplinary science and technology where small amounts... 2. Materials and methods. The lipids egg phosphatidylcholine (EPC),... 3. ...Author: Tiago Albertini Balbino, Adriano Rodrigues Azzoni, Lucimara Gaziola de la Torre
https://www.nature.com/articles/srep03155
Nov 06, 2013 · (A) A microfluidic cross-flow droplet generator chip is used to produce emulsified aqueous droplets containing the polymeric gene carrier and nucleic acids. …Author: Christopher L. Grigsby, Yi-Ping Ho, Chao Lin, Johan F. J. Engbersen, Kam W. Leong, Kam W. Leong
https://www.nature.com/articles/s41598-020-63172-8
There are a few attempts later that look into its potential for promotion of gene delivery ... microfluidic electroporation approach with a combination of nanosecond and millisecond pulses to ...
https://www.tandfonline.com/doi/figure/10.1080/14712598.2018.1416089?scroll=top&needAccess=true
(2018). AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials. Expert Opinion on Biological Therapy: Vol. 18, No. 3, pp ...
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