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https://www.pnas.org/content/pnas/100/24/13755.full.pdf
Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies Devin V. McAllister*, Ping M. Wang*, Shawn P. Davis*, Jung-Hwan Park*†, Paul J. Canatella*, Mark G. Allen‡, and Mark R. Prausnitz*†§Author: Devin V. McAllister, Ping M. Wang, Shawn P. Davis, Jung-Hwan Park, Paul J. Canatella, Mark G. Allen,...
https://www.pnas.org/content/100/24/13755
Nov 25, 2003 · Arrays of micrometer-scale needles could be used to deliver drugs, proteins, and particles across skin in a minimally invasive manner. We therefore developed microfabrication techniques for silicon, metal, and biodegradable polymer microneedle arrays having solid and hollow bores with tapered and beveled tips and feature sizes from 1 to 1,000 μm.Author: Devin V. McAllister, Ping M. Wang, Shawn P. Davis, Jung-Hwan Park, Paul J. Canatella, Mark G. Allen,...
https://www.ncbi.nlm.nih.gov/pubmed/14623977
Nov 25, 2003 · Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies. McAllister DV(1), Wang PM, Davis SP, Park JH, Canatella PJ, Allen MG, Prausnitz MR. Author information: (1)School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta 30332, USA.Author: Devin V. McAllister, Ping M. Wang, Shawn P. Davis, Jung-Hwan Park, Paul J. Canatella, Mark G. Allen,...
https://www.researchgate.net/publication/9003251_From_the_Cover_Microfabricated_needles_for_transdermal_delivery_of_macromolecules_and_nanoparticles_Fabrication_methods_and_transport_studies
From the Cover: Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies ... Microfabricated needles for transdermal delivery ...
https://www.sciencedirect.com/science/article/pii/S0022354915506242
Research Articles Microfabricated Microneedles: A Novel Approach to Transdermal Drug Delivery Sebastien Henry, †‡ Devin V. McAllister, †§ Mark G. Allen, * ∥ [email protected] Mark R. Prausnitz, * ‡ § [email protected] Institute for Bioengineering and Bioscience, School of Chemical Engineering, School of Electrical and Computer Engineering, and School of ...Author: Sebastien Henry, Devin V. McAllister, Mark G. Allen, Mark R. Prausnitz
http://adsabs.harvard.edu/abs/2003PNAS..10013755M
Arrays of micrometer-scale needles could be used to deliver drugs, proteins, and particles across skin in a minimally invasive manner. We therefore developed microfabrication techniques for silicon, metal, and biodegradable polymer microneedle arrays having solid and hollow bores with tapered and beveled tips and feature sizes from 1 to 1,000 μm.
http://europepmc.org/articles/PMC283494
Nov 01, 2003 · Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies. ... The term “transdermal” delivery is typically used to refer to transport across epidermis to the capillaries below the dermal–epidermal junction (for systemic administration) and does not usually refer to ...
https://www.sciencedirect.com/science/article/pii/S0169409X03002394
The success of transdermal drug delivery has been severely limited by the inability of most drugs to enter the skin at therapeutically useful rates. Recently, the use of micron-scale needles in increasing skin permeability has been proposed and shown to dramatically …Author: Mark R Prausnitz
https://www.annualreviews.org/doi/abs/10.1146/annurev.bioeng.2.1.289
Finally, microhypodermic needles and microneedles for transdermal drug delivery have been developed to reduce needle insertion pain and tissue trauma and to provide controlled delivery across the skin. These needles have been shown to be robust enough to penetrate skin and dramatically increase skin permeability to macromolecules.Author: Devin V. McAllister, Mark G. Allen, Mark R. Prausnitz
http://drugdelivery.chbe.gatech.edu/Papers/1998/Henry%20J%20Pharm%20Sci%201998.pdf
Microfabricated Microneedles: A Novel Approach to Transdermal Drug Delivery SEBASTIEN HENRY,†,‡ DEVIN V. MCALLISTER,‡,§ MARK G. ALLEN,*, AND MARK R. PRAUSNITZ*,‡,§ Contribution from Institute for Bioengineering and Bioscience, School of Chemical Engineering, School of Electrical and Computer Engineering, and School of Mechanical Engineering, Georgia Institute of …
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