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https://www.sciencedirect.com/science/article/pii/S0022354915506242
Research Articles Microfabricated Microneedles: A Novel Approach to Transdermal Drug Delivery Sebastien Henry, †‡ Devin V. McAllister, †§ Mark G. Allen, * ∥ [email protected] Mark R. Prausnitz, * ‡ § [email protected] Institute for Bioengineering and Bioscience, School of Chemical Engineering, School of Electrical and Computer Engineering, and School of ...Author: Sebastien Henry, Devin V. McAllister, Mark G. Allen, Mark R. Prausnitz
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201703606
In this feature article, microfabricated devices are described in terms of materials, mechanical design, working principles, and fabrication methods, all of which are key features for production of multifunctional, highly effective drug delivery systems.Author: Hongbin Zhang, John K. Jackson, Mu Chiao
https://www.researchgate.net/publication/316545164_Microfabricated_oral_drug_delivery_systems
Fig. 3: Working of a microfabricated drug delivery . system. INDIAN DRUGS 52 (11) NOVEMBER 2015 9 . drug release and hence enhances the oral delivery of . pharmaceuticals 1,10.
https://www.sciencedirect.com/science/article/pii/S0378517305006460
These microfabricated drug delivery devices can enable efficient drug delivery that was unattainable with conventional drug delivery techniques, resulting in the enhancement of the therapeutic activity of a drug. The future of drug delivery is assured to be significantly influenced by microfabrication technologies.Author: J. Zachary Hilt, Nicholas A. Peppas
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906704/
Drug delivery and/or biological fluid sampling mediated by hollow MNs . HMNs consisting of a fine bore can be integrated with a drug solution unit for continuous drug delivery or can be used for biological fluid sampling, unlike the replacement of SMNs with traditional drug-loaded patches for drug delivery.Author: Ryan F. Donnelly, Thakur Raghu Raj Singh, A. David Woolfson
https://www.mdpi.com/1996-1944/9/8/646/htm
Additionally, microfabricated vaccine delivery systems are presented due to the great impact they can have in obtaining a cold chain-free vaccine, with long-term stability. Microfabrication will continue to offer new, alternative solutions for the development of smart, advanced drug delivery systems.Author: Brendan Koch, Ilaria Rubino, Fu-Shi Quan, Bongyoung Yoo, Hyo-Jick Choi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534972/
May 01, 2012 · For example, the microfabricated oral drug delivery system can be manufactured to have increased contact with the intestinal wall, while minimizing shear disturbances and allowing for unidirectional drug release from a protected reservoir to enhance their retention in the body.Author: Shilpa Sant, Shilpa Sant, Shilpa Sant, Sarah L. Tao, Omar Z. Fisher, Qiaobing Xu, Nicholas A. Peppas...
https://www.ee.ucla.edu/events/microfabricated-microdevices-for-drug-delivery-vaccination-and-other-biomedical-applications/
Novel formulations will be emphasized that control drug transport during and after injection. Overall, this presentation will use these two case studies to demonstrate the ability of microfabricated microdevices to be translated from device design and fabrication through human clinical trials.
https://www.annualreviews.org/doi/10.1146/annurev.bioeng.2.1.289
By incorporating techniques adapted from the microelectronics industry, the field of microfabrication has allowed the creation of microneedles, which have the potential to improve existing biological-laboratory and medical devices and to enable novel devices for gene and drug delivery. Dense arrays of microneedles have been used to deliver DNA into cells. Many cells are treated at once, which ...Author: Devin V. McAllister, Mark G. Allen, Mark R. Prausnitz
http://drugdelivery.chbe.gatech.edu/Papers/1998/Henry%20J%20Pharm%20Sci%201998.pdf
Microfabricated Microneedles: A Novel Approach to Transdermal Drug Delivery SEBASTIEN HENRY,†,‡ DEVIN V. MCALLISTER,‡,§ MARK G. ALLEN,*, AND MARK R. PRAUSNITZ*,‡,§ Contribution from Institute for Bioengineering and Bioscience, School of Chemical Engineering, School of Electrical and Computer Engineering, and School of Mechanical Engineering, Georgia Institute of …
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