We have collected information about Mesenchymal Stem Cell Drug Delivery for you. Follow the links to find out details on Mesenchymal Stem Cell Drug Delivery.
https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/sctm.18-0024
Abstract The development of mesenchymal stem cells (MSCs) as cell‐based drug delivery vectors for numerous clinical indications, including cancer, has significant promise. However, a considerable c...
https://www.ncbi.nlm.nih.gov/pubmed/30070053
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for numerous clinical indications, including cancer, has significant promise. However, a considerable challenge for effective translation of these approaches is the limited tumor tropism and broad biodistribution observed using conventional MSCs, which raises ...Author: Timothy E. G. Krueger, Daniel L. J. Thorek, Samuel R. Denmeade, John T. Isaacs, W. Nathaniel Brennen
https://www.sciencedirect.com/science/article/pii/S0168365918307223
Although nanoparticle-based drug delivery exhibits great potential, there are some challenges facing like rapid plasma clearance, triggering or aggravation of immune response, etc. Herein, cell-based targeted drug delivery systems have drawn more and more attention owing to low immunogenicity and intrinsic mutation rate, and innate ability to ...Author: Hong-Hui Wu, Yi Zhou, Yasuhiko Tabata, Jian-Qing Gao
https://www.sciencedirect.com/science/article/pii/S0169409X12002128
Mesenchymal stem cell (MSC) as the source of exosomes for drug delivery. Successful exploitation of exosomes as drug delivery vehicles is likely to leverage on a combination of factors that include their natural intrinsic properties, amenability to modifications to supplement or enhance these properties, and scalability of a GMP manufacture ...Author: Ronne Wee Yeh Yeo, Ronne Wee Yeh Yeo, Ruenn Chai Lai, Bin Zhang, Soon Sim Tan, Yijun Yin, Bao Ju Teh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991625/
Sep 30, 2010 · Mesenchymal stem cells (MSCs) possess a set of several fairly unique properties which make them ideally suited both for cellular therapies/regenerative medicine, and as vehicles for gene and drug delivery. These include: 1) relative ease of isolation; ...Author: Christopher D. Porada, Graça Almeida-Porada
https://pubs.acs.org/doi/10.1021/acs.nanolett.8b04697
Mesenchymal stem cell (MSC) has been increasingly applied to cancer therapy because of its tumor-tropic capability. However, short retention at target tissue and limited payload option hinder the progress of MSC-based cancer therapy. Herein, we proposed a hybrid spheroid/nanomedicine system, comprising MSC spheroid entrapping drug-loaded nanocomposite, to address these limitations. Spheroid ...Author: Smruthi Suryaprakash, Yeh-Hsing Lao, Hyeon-Yeol Cho, Mingqiang Li, Ha Yeun Ji, Dan Shao, Hanze Hu, C...
http://www.eurekaselect.com/111736/article
Keywords:Cancer therapy, drug delivery, mesenchymal stem cells. Abstract:Self renewal, extensive proliferation and multilineage differentiation ability in vitro and in vivo make mesenchymal stem cells (MSCs) powerful tools for tissue engineering. Beyond their potential uses in regenerative medicine, an emerging field of research aims to utilize ...
https://www.researchgate.net/publication/236922540_Mesenchymal_Stem_Cells_for_Anti-Cancer_Drug_Delivery
Mesenchymal stem cells (MSCs) have inherent tumor-tropic and migratory properties, which allow them to serve as vehicles for targeted drug delivery systems for isolated tumors and metastatic diseases.
http://orion.bme.columbia.edu/leonglab/publications/pdf/2015_JSP_Methods.pdf
Engineering mesenchymal stem cells for regenerative medicine and drug delivery Ji Sun Park1, Smruthi Suryaprakash1, Yeh-Hsing Lao1, Kam W. Leong⇑ Department of Biomedical Engineering, Columbia University, New York, NY 10027, United States
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(20)30016-4
Mesenchymal stromal cells (MSCs) possess several fairly unique properties that, when combined, make them ideally suited for cellular-based immunotherapy and as vehicles for gene and drug delivery for a wide range of diseases and disorders. Key among these are: (1) their relative ease of isolation from a variety of tissues; (2) the ability to be expanded in culture without a loss of ...Author: Graça Almeida-Porada, Anthony J. Atala, Christopher D. Porada
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