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https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
3.4.1 Transdermal Drug Delivery System. Electrospun NFs can also be utilized as a transdermal drug delivery system (TDDS). A TDDS is designed to facilitate delivery through the skin. It is an alternative way of delivering sensitive drugs that are greatly affected by first-pass metabolism.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://www.researchgate.net/publication/261759007_TRANSDERMAL_DRUG_DELIVERY_SYSTEM_A_REVIEW
Transdermal drug delivery system (TDDS) is topically administered dosage form in the form of patches which deliver drugs for systemic effects at a predetermined and controlled rate.
https://www.drugs.com/newdrugs/fda-approves-secuado-asenapine-transdermal-adults-schizophrenia-5079.html
The once-daily transdermal drug delivery system (TDDS) provides sustained concentrations during wear time (24 hours) 2 of the atypical antipsychotic drug asenapine, a well-established treatment for schizophrenia. A transdermal patch may help to mitigate some of the challenges patients face with the management of their schizophrenia. 2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293348/
Dec 13, 2011 · “The transdermal drug delivery system (TDDS) can be defined as a delivery device, which upon application on a suitable skin surface will be able to deliver the drug at controlled rate into the systemic circulation at clinically sufficient concentrations to ensure therapeutic efficacy over a prolonged period of time” [10, 11]. The benefits ...
https://www.3m.com/3M/en_US/drug-delivery-systems-us/
Take advantage of our more than 50 years of global pharmaceutical development and manufacturing services experience. Work hand-in-hand using proven inhalation, transdermal, oral and topical manufacturing expertise from feasibility to market -- all while ensuring the highest standards of manufactured product delivery in drug delivery systems.
http://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
12.2 Polymer matrix: Polymers are the backbone of transdermal drug delivery system. System for transdermal delivery are fabricated as multi layered polymeric laminates in ehich a drug reservoir or a drug polymer matrix is sandwitched between two polymeric layers, an outer impervious backing layer that prevents the loss of drug through the backing surface and an inner polymeric layer that ...
https://www.mdpi.com/journal/pharmaceutics/special_issues/transd_drug_deliv_syst
The skin permeation rate of drugs is generally slow; accordingly, drugs applied as Transdermal Delivery Systems (TDS) are limited to about 20. Early works on TDS mostly focused on enhancing drug permeability through the stratum corneum to pave the way for TDS-containing drugs of varying physicochemical properties.
https://www.sciencedirect.com/topics/medicine-and-dentistry/transdermal-drug-administration
Transdermal drug delivery systems (TDDS) have generated extensive interest as a preferred alternative to oral drug delivery and hypodermic injections, ever since the first scopolamine transdermal patch for motion sickness was approved by the US Food and Drug Administration in 1979 [1].
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