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https://www.slideshare.net/ganapati123/activation-modulated-drug-delivery-systems
Mar 18, 2013 · Mechanically activated drug delivery system Equipped with a mechanically activated pumping system A measured dose of drug formulation is reproducibly delivered The volume of solution delivered is controllable, as small as 10-100µl Volume of solution delivered is independent of the force & duration of activation applied as well as the solution ...
https://pubs.acs.org/doi/abs/10.1021/acs.chemrev.6b00369
Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical- or physical-based stimuli-responsive formulations or devices for controlled drug release have been developed. Among them, the emerging mechanical force-based stimulus offers a convenient and robust controlled drug release ...Author: Yuqi Zhang, Jicheng Yu, Hunter N. Bomba, Yong Zhu, Zhen Gu
https://www.slideshare.net/KailasMali1/ratecontrolled-drug-delivery-system
Apr 21, 2018 · Mechanically- activated drug delivery systems In this type, drug reservoir is in solution form retained in a container equipped with mechanically activated pumping system. A measured dose of the drug formulation is reproducible delivered in to a body cavity, for ex.
https://wyss.harvard.edu/technology/nanorx-mechanically-activated-drug-targeting/
A nanoscale delivery technology that concentrate drugs at sites of vascular occlusions or can be targeted using ultrasound. The Wyss team has developed a novel drug targeting nanotechnology that is activated locally by mechanical forces, either endogenous high shear stresses in blood created by vascular occlusion or mechanical energy applied locally using low-energy ultrasound radiation.
https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201807909
Mechanically Activated Microcapsules for “On‐Demand” Drug Delivery in Dynamically Loaded Musculoskeletal Tissues. Bhavana Mohanraj. Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104 USA ... To demonstrate the feasibility of this delivery system, an engineered ...Author: Bhavana Mohanraj, Bhavana Mohanraj, Gang Duan, Ana Peredo, Ana Peredo, Miju Kim, Fuquan Tu, Daeyeon ...
https://www.ncbi.nlm.nih.gov/pubmed/27680291
Oct 12, 2016 · The relevant DDS can be activated to promote drug release by different types of mechanical stimuli, including compressive force, tensile force, and shear force as well as indirect formats, remotely triggered by ultrasound and magnetic field. In this review, we provide an overview of recent advances in mechanically activated DDS.Author: Yuqi Zhang, Jicheng Yu, Hunter N. Bomba, Yong Zhu, Zhen Gu
http://www.authorstream.com/Presentation/jijothomaschirayil-2475868-controlled-drug-delivery-system/
Apr 29, 2015 · Mechanically activated drug delivery system : Mechanically activated drug delivery system In this type, drug reservoir is in solution form retained in a container equipped with mechanically activated pumping system. A measured dose of the drug formulation is reproducible delivered in to …
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