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http://jpsbr.org/index_htm_files/3_1151.pdf
controlled release drug delivery system can be are major advance toward solving problems concerning targeting of a drug to a specific organ or a tissue and controlling the rate of a drug delivery to the target site. Matrix system are favoured because of theirFile Size: 679KB
https://www.researchgate.net/publication/265673564_Matrix_Type_Drug_Delivery_System_A_Review
INTRODUCTION The goal of any drug delivery system is to provide a therapeutic amount of drug to the proper site in the body to achieve promptly and then maintain the desired drug concentration i.e ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648939/
Nov 04, 2012 · Oral controlled release systems. Historically, oral drug administration has been the predominant route for drug delivery. It is known to be the most popular route of drug administration due to the fact the gastrointestinal physiology offers more flexibility in dosage form design than most other routes (Chen et al. 2010, Gupta and Robinson 1992, Maderuelo et al. 2011, Tongwen and Binglin 1998).Author: Ali Nokhodchi, Shaista Raja, Pryia Patel, Kofi Asare-Addo
https://pdfs.semanticscholar.org/ded3/14e2b3d73d055388f0dea38af65c4cb68d47.pdf
The controlled release of a drug from matrix type polymeric drug delivery system is essentially governed by Fick’s law of diffusion: JD = D dc/dx Where, JD = This usually includes waxflux of diffusion across a plane surface of unit area D = is diffusibility of drug molecule, dc/dx = …
https://www.researchgate.net/profile/Arjun_Sai_Sreekar_Aeila/publication/338427577_SUSTAINED_RELEASE_MATRIX_TYPE_DRUG_DELIVERY_SYSTEM_AN_OVERVIEW/links/5e1479ac92851c8364b60afe/SUSTAINED-RELEASE-MATRIX-TYPE-DRUG-DELIVERY-SYSTEM-AN-OVERVIEW.pdf
Sustained release matrix type drug delivery system is the novel drug delivery system (NDDS) which plays an important role in improving the therapeutic effectiveness of the drugs by
https://www.ncbi.nlm.nih.gov/pubmed/27677866
The present study aimed to develop matrix-type transdermal drug delivery system (TDDS) of metoprolol tartrate using polyvinyl pyrrolidone (PVP) and polyvinyl alcohol (PVA). The transdermal films were evaluated for physical parameters, Fourier transform infrared spectroscopy analysis (FTIR), differential scanning calorimetry (DSC), in vitro drug ...Author: Venkata Ramana Malipeddi, Rajendra Awasthi, Daniela Dal Molim Ghisleni, Marina de Souza Braga, Irene...
https://en.wikipedia.org/wiki/Modified-release_dosage
Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).. Sustained-release dosage forms are dosage forms designed to release (liberate) a drug at a ...
https://www.mddionline.com/polymers-controlled-drug-delivery
As the release continues, its rate normally decreases with this type of system, since the active agent has a progressively longer distance to travel and therefore requires a longer diffusion time to release. Figure 2. Drug delivery from a typical matrix drug delivery system.
https://journal.pda.org/content/64/1/44
Jan 01, 2010 · The purpose of the investigation was to develop and evaluate matrix-type transdermal drug delivery systems (TDDSs) of trandolapril. Matrix-type TDDSs of trandolapril were prepared by solvent evaporation technique. Eight formulations (composed of Eudragit RL 100 and Hydroxypropyl methyl cellulose 15 cps at a ratios of 2:8, 4:6, 6:4, 8:2 in formulations A1, A2, A3, A4; and Eudragit RS …Author: Mamatha Tirunagari, Venkateswara Rao Jangala, Mukkanti Khagga, Ramesh Gannu
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