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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296090/
Oct 09, 2014 · A lymphatic targeted drug delivery system with a unique physiological disposition provides an effective tool for the treatment of diseases related to the lymphatic system, such as tumor metastasis, inflammation, and infectious disease.Author: Xiao-Yu Zhang, Wei-Yue Lu
https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118833322.ch21
This chapter first gives a brief description of the lymphatic system, followed by a characterization of physicochemical properties of typical drug carriers and their influence on lymphatic uptake and transport, and then reviews the recent development of drug carriers for the lymphatic system delivery with a special focus on nano‐scaled ...Author: Qiuhong Yang, Laird Forrest
https://www.nature.com/articles/s41598-019-49386-5
Sep 13, 2019 · Use of a Lymphatic Drug Delivery System and Sonoporation to Target Malignant Metastatic Breast Cancer Cells Proliferating in the Marginal Sinuses Skip …Author: Shigeki Kato, Shigeki Kato, Yuko Shirai, Maya Sakamoto, Shiro Mori, Tetsuya Kodama
https://www.monash.edu/pharm/research/areas/drug-delivery/research-areas/drug-delivery/lymphatic-absorption-and-targeted-delivery-to-the-lymphatic-system
Lymphatic absorption and targeted delivery to the lymphatic system Comprising a network of vessels, nodes and tissues throughout the vascular regions of the body, the lymphatic system plays a critical role in immune response, infection, fat metabolism, protein transport and cancer metastasis.
https://www.dovepress.com/advanced-drug-delivery-to-the-lymphatic-system-lipid-based-nanoformula-peer-reviewed-article-IJN
The lymphatic route also provides an option for the delivery of therapeutic molecules, such as drugs to treat cancer and human immunodeficiency virus, which can travel through the lymphatic system. Lymphatic imaging is useful in evaluating disease states and treatment plans for progressive diseases of the lymph system.
https://biomaterialsres.biomedcentral.com/articles/10.1186/s40824-016-0083-1
Nov 23, 2016 · Lipophilic drugs are known to be transported via the lymphatic system. The intestinal lymphatic pathway can bypass first-pass metabolism in the liver, thus increasing drug bioavailability. Furthermore, the co-administration of drugs with lipids can enhance their lymphatic transport [ 4 ].Author: Hyeji Ahn, Ji-Ho Park
http://www.hormonebalance.org/images/documents/McLennan%2005%20sub%20C%20delivery%20DDT.pdf
Lymphatic structure and function in relation to drug absorption from the interstitium In addition to its role in the absorption and transport of dietary lipids and highly lipophilic compounds (such as lipid soluble vitamins and some drugs) from the intestine to the systemic circulation, the lymphatic system …
https://www.sciencedirect.com/science/article/pii/S1818087613000135
Lymphatic drug delivery is receiving increasing attention because of its many advantages over other routes. This attention has included a number of trials evaluating transport of drug to the lymphatic system. Various lipid-based nanocarriers have been developed to selectively utilize the lymphatic system for drug delivery.Author: Hyeongmin Kim, Yeongseok Kim, Jaehwi Lee
http://www.authorstream.com/Presentation/swetha305-1565541-lymphatic-ppt/
Oct 15, 2012 · Lymphatic drug delivery is in its infancy, but localized treatments of the lymphatics will decrease systemic toxicities associated with cytotoxic chemotherapy and reduce recurrence owing to residual local disease.
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