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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296090/
Oct 09, 2014 · Nano drug delivery carriers that target the lymphatic system in recent literature include liposomes, nanoparticles, macromolecule polymers, polymer micelles (PMs), activated carbons, silicon, and nano-emulsions, among others. In this review, two types of carriers are discussed in detail.Author: Xiao-Yu Zhang, Wei-Yue Lu
https://www.nature.com/articles/s41598-019-49386-5
Sep 13, 2019 · Furthermore, the lymphatic administration of ALs and subsequent exposure to US might generate mechanical pressures that facilitate drug delivery to highly invasive breast cancer cells in …Author: Shigeki Kato, Shigeki Kato, Yuko Shirai, Maya Sakamoto, Shiro Mori, Tetsuya Kodama
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732201/
Jul 26, 2013 · The lymphatic route also provides an option for the delivery of therapeutic molecules, such as drugs to treat cancer and human immunodeficiency virus, which can travel through the lymphatic system. Lymphatic imaging is useful in evaluating disease states and treatment plans for progressive diseases of the lymph system.Author: Arshad Ali Khan, Jahanzeb Mudassir, Noratiqah Mohtar, Yusrida Darwis
https://www.monash.edu/pharm/research/areas/drug-delivery/research-areas/drug-delivery/lymphatic-absorption-and-targeted-delivery-to-the-lymphatic-system
Lymphatic drug transport is an area of particular interest and expertise at MIPS, and one in which our scientists are leading efforts worldwide. D4's focus here is on three programs: Drug transport into the lymphatic vessels of the small intestine The intestinal lymphatics—not...
https://www.nature.com/articles/s41578-019-0110-7
May 02, 2019 · Materials can be used as instructive delivery vehicles to achieve accumulation of drugs in the lymph nodes and to target specific lymph node …Author: Alex Schudel, Alex Schudel, David M. Francis, David M. Francis, Susan N. Thomas
http://www.hormonebalance.org/images/documents/McLennan%2005%20sub%20C%20delivery%20DDT.pdf
- Approaches allow lymphatic delivery of both small molecules and macromolecules - Flexibility and versatility in carrier characteristics - Localisation of drug in tissues (lymph, lymph nodes, tumour, etc.) - Removal of implantable devices allows immediate discontinuation of therapy
https://biomaterialsres.biomedcentral.com/articles/10.1186/s40824-016-0083-1
Nov 23, 2016 · Lipophilic drugs are known to be transported via the lymphatic system. The intestinal lymphatic pathway can bypass first-pass metabolism in the liver, thus increasing drug bioavailability. Furthermore, the co-administration of drugs with lipids can enhance their lymphatic transport [ 4 ].Author: Hyeji Ahn, Ji-Ho Park
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