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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
The development of drug delivery systems for pulmonary application requires a detailed knowledge of the lung in its healthy, as well as various diseased states. The lung is composed of more than 40 different cells. The human respiratory system is a complex organ …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733285/
May 30, 2019 · Lung delivery of IND/GLY 110/50 µg was consistent across various drug batches at a flow rate of 90 L/min (Table 2). The comparison of the APSD of detached drug particles entering the lungs with the APSD emitted from the inhaler showed a predominant filtering of particles larger than the mass median aerodynamic diameter ...Author: Myrna B. Dolovich, Andreas Kuttler, Thomas J. Dimke, Omar S. Usmani
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
Pulmonary drug delivery is getting more and more magnitude. This is on account of the specific physiological environment of the lung as an absorption and treatment organ. The development of inhalable insulin can be perceived as a milestone in pulmonary drug delivery.
https://www.sciencedirect.com/science/article/pii/S0168365920301681
Although lung delivery via local routes can considerably avoid drug distribution to other tissues, several drawbacks need to be addressed. Intratracheal injection is an invasive approach and is not highly acceptable in practical applications.Author: Junghyun Kim, Seulgi Jeon, Seong Jae Kang, Kyoung-Ran Kim, Hien Bao Dieu Thai, Seokyung Lee, Sehoon ...
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https://www.nature.com/articles/aps201734
May 01, 2017 · Lung cancer is the second most prevalent and the deadliest among all cancer types. Chemotherapy is recommended for lung cancers to control tumor growth and …Author: Sharad Mangal, Wei Gao, Tonglei Li, Qi (Tony) Zhou
https://home.liebertpub.com/publications/journal-of-aerosol-medicine-and-pulmonary-drug-delivery/24/overview
Journal of Aerosol Medicine and Pulmonary Drug Delivery is the only peer-reviewed journal delivering innovative, authoritative coverage of the health effects of inhaled aerosols and delivery of drugs through the pulmonary system. The Journal is a forum for leading experts, addressing novel topics such as aerosolized chemotherapy, aerosolized vaccines, methods to determine toxicities, and ...
https://www.nhlbi.nih.gov/events/2014/targeted-drug-delivery-lung-diseases
To date, precision therapeutics has primarily focused on oncologic applications. However, precision drug delivery for lung diseases is well-positioned to advance, given the emergence of novel drug delivery paradigms and the unique accessibility of pulmonary tissues via airway and vascular routes.
https://www.pharmatutor.org/articles/pulmonary-drug-delivery-a-review
ABOUT AUTHORS: Dr. N.V. Satheesh Madhav, Girish Dwivedi* Dehradun Institute of Technology, Faculty of Pharmacy Village Makkawala, Mussoorie Diversion Road, Dehradun-248009 *[email protected] ABSTRACT Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung both for site
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