Long-Acting Or Sustained Release Delivery Of Proteins Peptides

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Delivery of Peptides and Proteins via Long Acting ...

    https://rd.springer.com/chapter/10.1007%2F978-1-4614-0554-2_20
    Sep 13, 2011 · Sustained release implants usually provide a longer term delivery duration than long acting injections and can be categorized into bioerodible systems (rods and cylinders) and implantable devices.Author: Cynthia L. Stevenson, Christopher A. Rhodes, Steven J. Prestrelski

Target specific and long-acting delivery of protein ...

    https://www.sciencedirect.com/science/article/pii/S0168365909006269
    Third, the applications of HA derivatives are described to novel delivery of biopharmaceuticals: target specific intracellular delivery of nucleotide therapeutics, long-acting conjugation of peptide and protein therapeutics, and sustained release depot systems of protein therapeutics.Author: Eun Ju Oh, Kitae Park, Ki Su Kim, Jiseok Kim, Jeong-A Yang, Ji-Hyun Kong, Min Young Lee, Allan S. Ho...

Sustained-Release Delivery of Octreotide from ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225556/
    Sep 27, 2011 · Moreover, PLGA microspheres have been used successfully to deliver therapeutic peptides and proteins in a sustained-release manner, and many commercial long-acting release (LAR ®) drug formulations of microspheres are available on the market (e.g., Lupron Depot ®, Zoladex ®, Decapeptyl ®, Eligard ®, Enantone ®, Trenantone ®, Risperdal Consta ® and Profact ®) (17–27). Injectable …Author: Yun-Seok Rhee, Yun-Seok Rhee, MinJi Sohn, Byung H. Woo, B. C. Thanoo, Patrick P. DeLuca, Heidi M. Ma...

Parenteral sustained release of peptides and proteins ...

    https://ddfevent.com/media/12248/simon-bjerregaard.pdf
    friendly drug delivery ... Long acting injectables for peptide and proteins. Aqueous suspensions Low soluble salts/crystals Zinc complex ... ‣Large potential within sustained release of peptides and proteins which could be realized with novel technologies. 21 Future directions

Carrier Mediated Systemic Delivery of Protein and Peptide ...

    http://www.eurekaselect.com/144103/article
    Keywords:Drug delivery system, control release, sustain release, systemic delivery, protein and peptide therapeutic, route of administration, insulin. Abstract:Over the last few decades proteins and peptide therapeutics have occupied an enormous fraction of pharmaceutical industry. Despite their high potential as therapeutics, the big challenge often encountered is the effective administration and bioavailability of protein therapeutics …Author: Rahela Zaman, Iekhan Othman, Ezharul Hoque Chowdhury

Injectable implants for the sustained release of protein ...

    https://www.sciencedirect.com/science/article/pii/S1359644613000354
    Cytoryn™ is a ReGel/interleukin-2 intratumoral injection that has shown sustained release for 72–96 h and presents a promising platform for cancer immunotherapy . hGHD-1 is a protein delivery system for sustained release of human growth hormone from ReGel , whereas OncoGel™ is an intralesion depot system used for sustained release of paclitaxel over six weeks .Author: Priyanka Agarwal, Ilva D. Rupenthal

ORAL PEPTIDE DELIVERY: TECHNOLOGY LANDSCAPE & CURRENT ...

    https://www.ondrugdelivery.com/review-oral-peptide-delivery/
    Ipsen is a global, speciality driven pharma company with interests in oncology, neuroscience and rare diseases. Its drug delivery systems expertise includes systems for intracellular delivery of peptides and sustained release / long acting peptide formulations.

Ultra-long-acting tunable biodegradable and removable ...

    https://www.nature.com/articles/s41467-019-12141-5
    Sep 20, 2019 · The goal of this work was to develop a delivery system that can offer ultra-long-acting drug release by (1) providing flexibility in the choice of active ingredient, (2) sustained release for weeks or months, (3) the ability to be surgically removed in case of an allergic or adverse reaction, (4) and the ability to integrate multiple drugs.Author: S. Rahima Benhabbour, Martina Kovarova, Clinton Jones, Daijha J. Copeland, Roopali Shrivastava, Mich...

DELIVERY OF THERAPEUTIC PROTEINS - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857543/
    Falmel’s Medusa® polymer, made of glutamic acid and vitamin E, is one such vehicle that is amphiphilic in nature and forms nanoparticle in water. 112 Currently various protein-polymer compounds are at various stages of clinical trials and have demonstrated long acting sustained release of these protein drugs.Author: Dipak S. Pisal, Matthew P. Kosloski, Sathy V. Balu-Iyer

Carrier Mediated Systemic Delivery of Protein and Peptide ...

    https://www.researchgate.net/publication/305636118_Carrier_Mediated_Systemic_Delivery_of_Protein_and_Peptide_Therapeutics
    Use of NP mediated drug delivery to modulate PK and PD of a therapeutic is another approach to create long acting therapeutic formulations [7]. Drug delivery systems …

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