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https://www.ahajournals.org/doi/full/10.1161/CIRCINTERVENTIONS.110.961052
May 03, 2011 · Paclitaxel is a taxane derivative with antiproliferative properties that make it effective in treating coronary restenosis. 2 Paclitaxel has been used in most vascular beds, and several trials using different methods of local delivery for the treatment of lower-extremity peripheral arterial disease (PAD) have been recently reported. 3 – 5 The discussion that follows aims to (1) describe the characteristics of paclitaxel that make it suitable for local drug delivery…Author: Beau M. Hawkins, Thomas A. Hennebry
https://www.ncbi.nlm.nih.gov/pubmed/21540442
Local paclitaxel delivery for treatment of peripheral arterial disease. Hawkins BM(1), Hennebry TA. Author information: (1)Cardiovascular Section, Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.Author: Beau M. Hawkins, Thomas A. Hennebry
https://onlinelibrary.wiley.com/doi/pdf/10.1111/eci.12407
paclitaxel local delivery for the treatment of peripheral artery disease. Chemical properties of paclitaxel Paclitaxel is a white crystalline powder with chemical formula C 47H 51NO 14 and a molecular weight of 853 9. Paclitaxel is highly lipophilic, insoluble in water, and melts at a temperature of 216–217 °C.Author: Vivian G. Ng, Carlos Mena, Cody Pietras, Alexandra J. Lansky
https://onlinelibrary.wiley.com/doi/full/10.1111/eci.12407
Three main local paclitaxel delivery mechanisms for the prevention or treatment of stenosis, restenosis or occlusion in the peripheral vessels exist: DESs, drug‐coated balloons (DCBs) and local liquid delivery …Author: Vivian G. Ng, Carlos Mena, Cody Pietras, Alexandra J. Lansky
https://www.ahajournals.org/doi/abs/10.1161/CIRCINTERVENTIONS.110.961052
Close Drawer Menu Open Drawer Menu Home. AHA Journals. AHA Journals Home; Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) Journal Home; Current Issue; See All IssuesAuthor: Beau M. Hawkins, Thomas A. Hennebry
https://www.researchgate.net/publication/51096300_Local_Paclitaxel_Delivery_for_Treatment_of_Peripheral_Arterial_Disease
Local Paclitaxel Delivery for Treatment of Peripheral Arterial Disease. Local drug delivery is the process by which therapeutic agents are administered to targeted segments of the circulatory system to treat vascular disease.
https://www.fda.gov/medical-devices/letters-health-care-providers/august-7-2019-update-treatment-peripheral-arterial-disease-paclitaxel-coated-balloons-and-paclitaxel
Aug 07, 2019 · August 7, 2019 UPDATE: Treatment of Peripheral Arterial Disease with Paclitaxel-Coated Balloons and Paclitaxel-Eluting Stents Potentially Associated with Increased Mortality
https://www.researchgate.net/publication/271275401_Local_delivery_of_paclitaxel_in_the_treatment_of_peripheral_arterial_disease
Local delivery of paclitaxel in the treatment of peripheral arterial disease. Background Despite advancements from balloon angioplasty to drug-eluting stents, primary patency rates after endovascular revascularization of peripheral artery disease …
https://www.nejm.org/doi/full/10.1056/NEJMoa0706356
Drug-eluting stents reduce restenosis in coronary arteries, but clinical trials have failed to prove their efficacy in peripheral arteries. We investigated the use of paclitaxel-coated angioplasty balloons and paclitaxel dissolved in the angiographic contrast medium during angioplasty of the leg.Author: Gunnar Tepe, Thomas Zeller, Thomas Albrecht, Stephan Heller, Uwe Schwarzwälder, Jean-Paul Beregi, M....
https://clinicaltrials.gov/ct2/show/NCT03858764
Mar 01, 2019 · Local Paclitaxel Delivery to Prevent Restenosis in Peripheral Arterial Disease (ResTAP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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