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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/self-microemulsifying-drug-delivery-system
Formulations that are developed using liquid lipid exist as either simple emulsions or self-emulsifying drug delivery systems (SEDDS). Depending upon the size, they are called as self-microemulsifying drug delivery system (SMEDDS) or self-nanoemulsifying drug delivery system (SNEDDS). SEDDS are isotropic mixtures of oils, surfactants, cosurfactants, and drug substances.
https://www.researchgate.net/publication/271608841_Emulsion-based_Drug_Delivery_Systems
Emulsion-based Drug Delivery Systems. A new solid-in-oil-in-water (S/O/W) emulsion consisting of edible surfactants, an edible oil, and a water-soluble drug has been developed for oral administration of peptide/protein drugs. Insulin, which is a hydrophilic macromoleclule, was converted into a lipophilic complex using edible surfactants.
https://www.longdom.org/open-access/selfemulsifying-drug-delivery-systems-sedds-in-pharmaceuticaldevelopment-2090-4568-1000130.pdf
Lipid-based formulations, such as Self-Emulsifying Drug Delivery Systems (SEDDS), are an important tool for lipophilic drugs and offer the potential for enhancing drug …File Size: 540KB
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2014.896058
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to formulate poor water soluble compounds for bioavailability enhancement. However, certain limitations are associated with SMEDDS formulations which include in vivo drug precipitation,
https://www.sciencedirect.com/science/article/pii/S2211383513000919
Depending upon the size of the emulsion particles, these systems can be further classified as self-micro emulsifying drug delivery systems (SMEDDS) or self-nano emulsifying drug delivery systems (SNEDDS). The formulation generally consists of drug, oily vehicle, surfactant, co …Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1191.pdf
Both SEDDSs and SMEDDSs have distinct features associated with improved drug delivery properties. SEDDS formulations can be simple binary systems: lipophilic phase and drug, or lipophilic phase, surfactant and drug. The formation of a SMEDDS requires …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888743/
Dec 26, 2013 · The attempts of various scientists to transform the liquid self-emulsifying drug delivery systems (SEDDS) to solid-SEDDS by adsorption, spray drying, lyophilization, melt granulation, extrusion, and so forth to formulate various dosage forms like self emulsifying capsules, tablets, controlled release pellets, beads, microspheres, nanoparticles, suppositories, implants, and so forth …Author: Shweta Gupta, Rajesh Kesarla, Abdelwahab Omri
https://www.mdpi.com/2079-4983/9/1/11/pdf
throughout the body, followed by targeted delivery. Judicious design of drug delivery systems leads to improved bioavailability, patient compliance and therapeutic outcomes. The rich phase behavior (micelles, hydrogels, lyotropic liquid crystals, etc.) of poloxamers makes them amenable to multiple types of processing and various product forms.
https://www.studyread.com/types-of-emulsions/
Emulsions are bi-phasic liquid solutions. They are used for drug delivery in medicine, cleaning of oil and greasy surfaces, storage of substances, etc. The routes of medication administration by which emulsions are given include by oral, parenteral and even few topical preparations (creams).
https://www.hindawi.com/journals/jphar/2014/801820/
Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
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