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https://www.hindawi.com/journals/jdd/2011/326497/
Various anionic liposomes have been characterized for gene delivery in a small number of cell types including CHO cells and primary hippocampal neurons [8, 66, 68, 69].While such investigations are novel, overall knowledge regarding anionic lipofection is as yet limited due to a lack of extensive testing; DNA entrapment in anionic liposomes is still inefficient, and cytotoxicity data remain ...Author: Daniel A. Balazs, Wt. Godbey
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · These characteristics have led to applications in chemical and biochemical analytics, cosmetics, food technologies, and drug and gene delivery [7, 8]. There are numerous lipid formulations for each of these applications. However, this review will focus primarily on the use of liposomes for …Author: Daniel A. Balazs, Wt. Godbey
https://www.researchgate.net/publication/12950633_Liposomes_as_a_gene_delivery_system
Since liposomes can easily bind to the cell surface, they have been used as nonviral vectors for gene delivery (Ropert, 1999). Unlike nonviral vectors, viral gene delivery systems have improved ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Liposomal drug delivery systems are very effective in the delivery of vaccines and genes due to their adjuvant property and targeting ability which elicit the immune response of the body through antibody formation and corrected gene inputs. Along with this, the mechanism of vaccine and gene delivery is …
https://www.crcpress.com/Liposomes-in-Gene-Delivery/Lasic/p/book/9780849331091
Many specialists are not familiar with both drug delivery and the molecular biology of DNA vectors. Liposomes in Gene Delivery covers both-molecular biologists will gain a basic knowledge of lipids, liposomes, and other gene delivery vehicles; lipid and drug delivery scientists will better understan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722627/
Although gene therapy as a treatment for disease holds great promise, progress in developing effective clinical protocols has been slow. The problem lies in the development of safe and efficient gene-delivery systems. This review will evaluate the problems and the potential solutions in this new field of medicine.
https://www.nature.com/articles/s41417-019-0141-7
Nov 02, 2019 · Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The surface properties of liposomal carriers, including …Author: Shuai Zhen, Shuai Zhen, Xu Li, Xu Li
https://www.slideshare.net/DurgaBhavani60/liposomal-gene-delivery-system
Jul 14, 2019 · LIPOSOMAL GENE DELIVERY SYSTEMS: INTRODUCTION: Liposomes have been explored as a delivery system for DNA as early as in 1979. The encapsulation of plasmid DNA into liposomes and the introduction of poliovirus RNA and SV40 DNA into cells via liposomes were reported between 1979 and 1980. These are vesicles that can easily merge with the cell ...
https://www.slideshare.net/pratibhaSharma97/liposome-mediated-gene-delivery
Jun 26, 2018 · • They are termed as pH sensitive due to destabilization at low pH. • cationic liposomes get inactivated and unstable in the presence of serum and exhibit cytotoxicity • Due to reduced toxicity and interference from serum proteins, pH-sensitive liposomes are considered as potential gene delivery vehicles than the cationic liposomes. 11.
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