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https://www.sciencedirect.com/science/article/abs/pii/0169409X9500016Z
Various routes of administration such as topical instillation, intravitreal, subconjunctival and systemic injection are also discussed. Significant progress has been made in these areas and a complete understanding of the liposome interaction with ocular tissues should enable the design of liposomal products suitable for ocular drug delivery.Author: Dale Meisner, Michael Mezei
https://www.sciencedirect.com/science/article/pii/0169409X9500016Z
3. Liposomal ocular delivery The development of liposomes for ocular drug delivery has not received as much attention as other routes of administration, and as such there is still no liposomal ophthalmic drug product on the market. Liposomes have been studied for ocular drug delivery by various approaches of administration [2-4,16].Author: Dale Meisner, Michael Mezei
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656938/
Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): in vitro characterization and improved corneal permeation. Yikang Dai, 1 Rui Zhou, 2 Lin Liu, 1 Yi Lu, 2 Jianping Qi, 2 and Wei Wu 2 ... When rabbit eyes were treated with a DiI perchlorate-loaded liposome suspension, liposomes containing bile salts showed ...Author: Yikang Dai, Rui Zhou, Lin Liu, Yi Lu, Jianping Qi, Wei Wu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099572/
Aug 08, 2013 · Vesicular drug delivery systems such as liposomes have been used in therapeutic approaches for ocular abnormalities. Efficacy of liposomes as a carrier for drugs depends upon various factors such as charge, rigidity, composition of the liposomal membrane, encapsulation efficiency and release rate ( Lee et al., 1985 ).Author: Ehab I. Taha, Magda H. El-Anazi, Ibrahim M. El-Bagory, Mohsen A. Bayomi
https://www.hindawi.com/journals/jdd/2011/863734/
Liposomal formulations were significantly explored over the last decade for the ophthalmic drug delivery applications. These formulations are mainly composed of phosphatidylcholine (PC) and other constituents such as cholesterol and lipid-conjugated hydrophilic polymers. Liposomes are biodegradable and biocompatible in nature. Current approaches for topical delivery of liposomes are focused on ...Author: Gyan P. Mishra, Mahuya Bagui, Viral Tamboli, Ashim K. Mitra
https://www.slideshare.net/uapnazmul/liposomal-drug-delivery-system
Aug 28, 2013 · Mechanism of liposomal drug delivery A liposome encapsulates a region of aqueous solution inside a hydrophobic membrane; dissolved hydrophilic solutes cannot readily pass through the lipids. Hydrophobic chemicals can be dissolved into the membrane, and in this way liposome can carry both hydrophobic molecules and hydrophilic molecules.
https://www.deepdyve.com/lp/elsevier/liposome-ocular-delivery-systems-Satr7MUbqQ
Liposome ocular delivery systems Liposome ocular delivery systems Meisner, Dale; Mezei, Michael 1995-08-01 00:00:00 Liposomes are microscopic vesicles composed of membrane-like lipid bilayers surrounding aqueous compartments. This unique feature imparts the ability of liposomes to encapsulate both lipophilic and hydrophilic compounds.
https://journals.sagepub.com/doi/abs/10.1177/1120672118769776
May 14, 2018 · In this review, we tried to focus on current research in ocular delivery of drug substances giving special emphasis to liposomal delivery system. A brief analysis of other novel ocular delivery systems, ocular physiology, and microbial sources of disease are also highlighted herein.Author: Arpita Bhattacharjee, Pranab J Das, Piya Adhikari, Daphisha Marbaniang, Paulami Pal, Subhabrata Ray,...
https://www.researchgate.net/publication/281515345_Liposomes_as_a_Novel_Ocular_Delivery_System_for_Brinzolamide_In_Vitro_and_In_Vivo_Studies
Liposomes as a Novel Ocular Delivery System for Brinzolamide: In Vitro. and ... were designed as novel ocular delivery systems integrating hyaluronic acid (HA) inside and surrounding vesicles by a ...
https://www.researchgate.net/publication/319377217_Liposomes_as_ocular_drug_delivery_platforms_A_review
Drug delivery to treat ocular disorders locally is a challenging endeavor. Traditional ocular dosage form - eye drops - exhibits poor availability, consequently inefficient therapeutic response.
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